PRELIMINARY COPY                                  SCHEDULE 14A
                                 (Rule 14a-101)(RULE 14A-101)

                     INFORMATION REQUIRED IN PROXY STATEMENT

                            SCHEDULE 14A INFORMATION

                Proxy Statement Pursuant to SectionPROXY STATEMENT PURSUANT TO SECTION 14(a) of the Securities
        Exchange Act ofOF THE
                         SECURITIES EXCHANGE ACT OF 1934 (Amendment No.             )

Filed by the Registrant [X]Registrant|X|
Filed by a Party other than the Registrant [ ]

Check the appropriate box:
[X][ ]  Preliminary Proxy Statement    [ ]  Confidential, for Use of the Commission
[X]  Definitive Proxy Statement          Only (as permitted by Rule 14a-
                                               6(e)14a-6(e)(2))
[ ]     Definitive Proxy Statement
[ ]  Definitive Additional Materials
[ ]  Soliciting Material Pursuant to Rule 14a-11(c) or Rule 14a-12

                             Cryomedical
Sciences,Biolife Solutions, Inc.
- --------------------------------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)


- --------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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       [X]|X|    No fee required.

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              the filing fee is calculated and state how it was determined):

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                             PRELIMINARY COPY
                   CRYOMEDICAL SCIENCES,BIOLIFE SOLUTIONS, INC.
                                1300 Piccard Drive, Suite 102
                    Rockville, Maryland 20850
                         _______________171 Front Street
                                 Owego, NY 13827
                                 --------------

                    NOTICE OF SPECIALANNUAL MEETING OF STOCKHOLDERS
                        To Be Held on December 16, 1998TO BE HELD ON SEPTEMBER 28, 2005

To the Stockholders of
CRYOMEDICAL SCIENCES,BIOLIFE SOLUTIONS, INC.

You areNotice is hereby  notifiedgiven  that a Specialthe  Annual  Meeting  of  Stockholders  of Cryomedical Sciences,BioLife
Solutions,  Inc., a Delaware  corporation (the  "Company"),  will be held at the
offices of the
Company, 1300 Piccard Drive, Suite 102, Rockville, Maryland
20850,Breslow & Walker,  LLP,  767 Third  Avenue,  New York,  NY 10017,  on
December 16, 1998,September  28, 2005,  at 10:00 a.m., Maryland time,am,  Eastern  Standard  Time,  for the  following
purposes:

       1.     To elect a board of four directors to (i) ratifyserve until the next Annual
              Meeting of Stockholders and until their successors are duly
              elected and qualified.

       2.     To approve each of the matters contained in a Plan of
Recapitalization and Financing (the "Plan") adopted and approved
by the Company's Board of Directors pursuant to the terms and
conditions of a Stock Purchase Agreement with ValorInvest, Ltd.
and required by the terms thereof to be submittedan amendment to the Company's stockholdersCertificate of
              Incorporation to increase the number of authorized shares of
              common stock from 25,000,000 to 100,000,000.

       3.     To approve an amendment to the Company's 1998 Stock Option Plan to
              increase the number of shares of common stock reserved for
              their approval, and (ii)issuance thereunder from 4,000,000 to 10,000,000.

       4.     To ratify the appointment of Aronson & Company to serve as
              independent auditors for the year ending December 31, 2005.

       5.     To transact such other business as may properly come before the
              meeting andor any and allpostponements or adjournments thereof.

        The Plan is comprised of each of the matters to be voted
on at the Meeting, and provides that the Company (i) amend its
Certificate of Incorporation to (a) effect a (1) one-for-five, (2) one
for six, (3) one for seven, (4) one for eight, (5) one for nine, (6)
one for ten, (7) one for eleven, (8) one for twelve, (9) one for
thirteen, (10) one for fourteen, (11) one for fifteen, or (12) one for
sixteen reverse stock split of the issued and outstanding shares of
common stock of the Company, par value $.001 per share
("Common Stock"), each of such alternatives to be approved by
the stockholders of the Company and one of such approved
alternatives to be chosen by the Board of Directors of the
Company, (b) reduce the number of authorized shares of Common
Stock from 50,000,000 shares to 25,000,000 shares, and (c) reduce
the authorized number of shares of Preferred Stock, par value
$.001 per share, from 9,378,800 shares to 1,000,000 shares, (ii)
adopt a 1998 Stock Option Plan, (iii) grant stock options/warrants
for approximately 19,780,000 shares (pre-reverse stock split) (of
which stock options/warrants for 19,155,000 shares (pre-reverse
stock split) have been granted, subject to stockholder approval),
exercisable at $.25 per share (pre-reverse stock split) to
management, others who have provided services to the Company,
and directors, to appropriately incentivize and compensate them,
and (iv) prepare and file a registration statement with the Securities
and Exchange Commission for the sale of securities by the
Company.  Each matter in the Plan will be voted on separately
and, if approved, may be effectuated by the Company.  However,
for the Plan to be approved, each matter in the Plan must be
approved. THE FAILURE TO APPROVE EACH MATTER IN
THE PLAN, AND THEREFORE THE PLAN, COULD HAVE
A MATERIAL ADVERSE EFFECT ON THE BUSINESS AND
FINANCIAL CONDITION OF THE COMPANY.  SEE
"PROXY STATEMENT - BACKGROUND."  Approval of a
matter requires a "FOR" vote on the accompanying proxy.  If no
choice is specified in the accompanying Proxy, the Proxy will be
voted "FOR" the matter.  A vote to "ABSTAIN" with respect to
a matter will have the same effect as a vote "AGAINST" the
matter.

        The foregoing items of business are more fully described
in the Proxy Statement accompanying this Notice.

The Board of Directors has fixed the close of business on October 23, 1998August 19, 2005 as the
record date for the  determination of stockholders  entitled to notice of and to
vote at the SpecialAnnual Meeting or any adjournments thereof.

ALL STOCKHOLDERS ARE CORDIALLY INVITED TO ATTEND THE SPECIALANNUAL MEETING.  WHETHER OR
NOT YOU PLAN TO ATTEND THE MEETING,  YOU ARE URGED TO COMPLETE,  SIGN,  AND DATE
THE ENCLOSED PROXY CARD AND RETURN IT PROMPTLY IN THE ENCLOSED ENVELOPE.  IF YOU
ATTEND  THE  MEETING,  YOU MAY VOTE YOUR  SHARES IN PERSON IF YOU WISH TO DO SO,
EVEN IF YOU HAVE SIGNED AND RETURNED YOUR PROXY CARD.

                                        By Order of the Board of Directors,

                                        Richard J. Reinhart, Ph.D.,-------------------------------
                                        John G. Baust, President

                                        and Chief Executive Officer

                                                               
        Rockville, Maryland
        November 2, 1998Owego, New York
                                        August 26, 2005

                  IT IS IMPORTANT THAT THE ENCLOSED PROXY FORM
                       BE COMPLETED AND RETURNED PROMPTLY


                             PRELIMINARY COPY
                   CRYOMEDICAL SCIENCES,BIOLIFE SOLUTIONS, INC.
                                1300 Piccard Drive, Suite 102
                    Rockville, Maryland 20850
                         _______________171 FRONT STREET
                                 OWEGO, NY 13827

                                 ---------------

                                 PROXY STATEMENT

                                 _______________

                 SPECIAL---------------

                         ANNUAL MEETING OF STOCKHOLDERS

                          December 16, 1998TO BE HELD SEPTEMBER 28, 2005

                             SOLICITATION OF PROXIES

This Proxy Statement is furnished in connection with the solicitation by the
Board of Directors of Cryomedical Sciences,BioLife Solutions, Inc., a Delaware corporation (the
"Company"), of proxies to be voted at a Specialthe Annual Meeting of Stockholders of the
Company to be held on December 16, 1998September 28, 2005 (the "Meeting"), at 10:00 a.m., Maryland time,Eastern
Standard Time, at the offices of the Company, 1300 Piccard
Drive, Suite 102, Rockville, Maryland 20850,Breslow & Walker, LLP, 767 Third Avenue, New
York, NY 10017, and at any adjournments thereof.  

        The close of business on October 23, 1998 has been
fixed as the record date for the determination of stockholders
entitled to notice of and to vote at the Meeting.  On that date
there were 33,454,302 shares of the Company's common stock,
par value $.001 per share ("Common Stock"), issued and
outstanding, each of which has one vote on each matter to be
presented at the Meeting (the "Proposals"), and 128 shares of the
Company's Series E Convertible Preferred Stock, par value
$.001 per share ("Preferred Stock"), issued and outstanding,
each of which has 10,000 votes on each Proposal.  The holders
of Common Stock and the holders of Preferred Stock will vote
together on the Proposals as if they held one class of stock.  The
holders of stock representing a majority of the votes entitled to
be cast at the Meeting, present in person or by proxy, will
constitute a quorum for the transaction of business at the Meeting
and any adjournments thereof. Approval of the Proposals to
amend the Company's Certificate of Incorporation (the
"Charter") to (i) effect a one-for-five, one-for-six, one-for-seven,
one-for-eight, one-for-nine, one-for-ten, one-for-eleven, one-for-
twelve, one-for-thirteen, one-for-fourteen, one-for-fifteen, or
one-for-sixteen reverse stock split of the issued and outstanding
Common Stock, with one of such approved alternatives to be
chosen by the Board of Directors of the Company (the "Reverse
Stock Split"), (ii) reduce the number of authorized shares of
Common Stock from 50,000,000 shares to 25,000,000 shares
(the "Common Stock Reduction"), and (iii) reduce the number
of authorized shares of Preferred Stock from 9,378,800 shares
to 1,000,000 shares (the Preferred Stock Reduction"), requires
the affirmative vote of the holders of stock representing a
majority of the votes entitled to be cast at the Meeting. Approval
of the Proposals to (i) ratify and approve the Company's 1998
Stock Option Plan (the "1998 Stock Option Plan"), (ii) ratify and
approve the grant of stock options/warrants to purchase
19,155,000 shares (pre-Reverse Stock Split) of Common Stock,
exercisable at $.25 per share (pre-Reverse Stock Split) to
management, others who have performed services for the
Company, and directors, to appropriately incentivize and/or
compensate them for the services provided to the Company (the
"Stock Option/Warrant Grant"), and (iii) approve the preparation
and filing of a registration statement with the Securities and
Exchange Commission for the sale of securities by the Company
(the "SEC Filing"), requires the affirmative vote of the holders
of stock representing a majority of shares present in person or
represented by proxy at the Meeting and entitled to vote thereon. 
All votes will be tabulated by the inspector(s) of election
appointed for the Meeting, who will separately tabulate
affirmative and negative votes, abstentions and broker non-votes. 
Abstentions will be counted towards the tabulation of votes cast
on the Proposals and will have the same effect as negative votes. 
Broker non-votes are counted towards a quorum, but are not
counted for any purpose in determining whether a Proposal has
been approved.

A form of proxy is enclosed for use at the Meeting. The proxy may be revoked by
a stockholder at any time before it is voted by execution of a proxy bearing a
later date or by written notice to the Secretary of the Company before the
Meeting, and any stockholder present at the Meeting may revoke his or her proxy
thereat and vote in person if he or she desires. When such proxy is properly
executed and returned, the shares of Common Stock, orSeries F Preferred Stock, and
Series G Preferred Stock it represents will be voted at the Meeting in
accordance with any instructions noted thereon. If no direction is indicated,
all shares of Common Stock, Series F Preferred Stock, and Series G Preferred
Stock represented by valid proxies received pursuant to this solicitation (and
not revoked prior to exercise) will be voted (i) FOR the proposed amendment toelection of the
Charter to effect
the Reverse Stock Split,nominees for directors named in this Proxy Statement, (ii) FOR the proposed
amendment to the CharterCertificate of Incorporation to effectincrease the Commonnumber of
authorized shares of common stock from 25,000,000 to 100,000,000 (the "Common
Stock Reduction,Increase"), (iii) FOR the proposed amendment to the CharterCompany's 1998 Stock
Option Plan to effectincrease the Preferrednumber of shares of Common Stock Reduction,reserved for
issuance thereunder from 4,000,000 to 10,000,000 (the "Plan Increase"), and (iv)
FOR the ratification and approval of the 1998
Stock Option Plan,appointment of Aronson & Company to serve as
independent auditors for the year ending December 31, 2005, and (v) FORin
accordance with the ratification and approvaljudgment of the Stock Option/Warrant Grant, and (vi) FORpersons named in the approval ofproxy as to such other
matters as may properly come before the SEC Filing.Meeting.

The cost for soliciting proxies on behalf of the Board of Directors will be
borne by the Company. In addition to solicitation by mail, proxies may be
solicited in person or by telephone, telefax, or cable by personnel of the
Company who will not receive any additional compensation for such solicitation.
The Company may reimburse brokers or other persons holding stock in their names
or the names of their nominees for the expenses of forwarding soliciting
material to their principals and obtaining their proxies. The approximate date
of mailing of this Proxy Statement and accompanying form of proxy is November 2, 1998.August 26,
2005.




BACKGROUND

        In connection withThe close of business on August 19, 2005 has been fixed as the record date for
the determination of stockholders entitled to notice of and to vote at the
Meeting. On that date there were 12,413,209 shares of the Company's efforts to raise capital,
the Company entered into aCommon
Stock, Purchase Agreement (the
"Stock Purchase Agreement") with ValorInvest, Ltd.par value $.001 per share ("ValorInvest"), a Geneva Switzerland based corporation
unrelated to the Company, pursuant to which, among other
things, ValorInvest (i) purchased from the Company, 128 Series
E Units at a price of $1,562.50 per Unit (an aggregate of
$200,000), and (ii) agreed to purchase, on or before December
28,1998, an additional 256 Series E Units at a price of
$1,562.50 per Unit (an aggregate of $400,000).  Each Unit
consists of one share of Series E Convertible Preferred Stock
("Series E PreferredCommon Stock"), convertible into 10,000issued and outstanding, each
of which has one vote on each matter to be presented at the Meeting (the
"Proposals"), 12,000 shares of Common Stock, and a warrant ("Series E Warrant") to purchase
5,000 shares of Common Stock at $.25 per share, the exercise
of which is subject to the consummation of a public offering of
(a), in the event the Common Stock is trading at a price of $.50
or more (pre-Reverse Stock Split), 16,000,000 shares (pre-
Reverse Stock Split) of Common Stock at not less than $.50 per
share (pre-Reverse Stock Split), or (b), in the event the Common
Stock is trading at a price of less than $.50 per share (pre-
Reverse Stock Split), 16,000 Series F Units at $500 per Series
F Unit.  Each Series F Unit shall consist of one share ofCompany's Series F Convertible Preferred
Stock, (to be authorized at such time)par value $.001 ("Series F Preferred Stock"), convertible into 1,000issued and outstanding,
each of which has four hundred (400) votes on each Proposal, and 55.125 shares
(pre-Reverseof the Company's Series G Convertible Preferred Stock, Split)par value $.001 ("Series
G Preferred Stock"), issued and outstanding, each of which has three hundred
twelve thousand five hundred (312,500) votes on each Proposal. The holders of
Common Stock, the holders of Series F Preferred Stock, and the holders of Series
G Preferred Stock will vote together on the proposals as if they held one class
of stock. The holders of stock representing a majority of the votes entitled to
one votebe cast at the Meeting, present in person or by proxy, will constitute a quorum
for each sharethe transaction of Common
Stock into which it is convertible,business at the Meeting and automatically convertible
into Common Stock ifany adjournments thereof.
Election of the closingDirectors requires a plurality of the votes entitled to be cast
by holders of stock represented in person or bid priceby proxy at the Meeting. Approval
of the Common Stock on any day is $.50 or more (pre-Reverse Stock Split), and
a warrant to purchase 250 shares (pre-Reverse Stock Split) of
Common Stock at $.75 per share (pre-Reverse Stock Split).  

        The Stock Purchase Agreement requires the Board of
Directors of the Company to adopt a Plan of Recapitalization and
Financing (the "Plan") and to submit the Plan to the Company's
stockholders for their approval.  Subject to the adoption by the
Company and its stockholders of the Plan, ValorInvest has
agreed to use its best efforts to arrange for a public offering
("Public Offering") (contemplated to be in Europe) of the
Company's securities through an underwriter (the "Underwriter")
to be designated or approved by ValorInvest.  Through
ValorInvest, the Company has obtained a letter of interest for a
Public Offering from a German Underwriter.  The letter does not
contain any commitment for a Public Offering, and any Public
Offering by such Underwriter, at the very least, would be subject
to the completion of due diligence by such Underwriter and
market conditions.  The terms of a Public Offering, if any,
would be as negotiated between the Company and the
Underwriter.  There can be no assurance that the Public
Offering, if consummated, would be on the terms set forth
above, or that a Public Offering would be consummated at all. 


        In the event the Plan is not approved by the Company
and its stockholders, there would be no requirement on the part
of ValorInvest to use its best efforts to arrange for the Public
Offering.  In addition, if the Plan is not approved by the
Company's stockholders by January 27, 1999, then, at the
request of ValorInvest, the Company must redeem the Series E
Units at a per Unit price equal to the price paid therefor plus an
additional amount determined by multiplying the price paid
therefor by a fraction, the denominator of which is the number
"120" and the numerator of which is the number of months
(rounded to a higher whole number) elapsed between September
30, 1998 and the redemption date.  Any such request by
ValorInvest would have a material adverse effect on the
business and financial condition of the Company.

        The Plan is comprised of each of the matters to be
voted on, including the Reverse Stock Split, the Common
Stock Reduction, the Preferred Stock Reduction, the 1998
Stock Option Plan, the Stock Option/Warrant Grant and the
SEC Filing.  Each matter in the Plan will be voted on separately
and, if approved, may be effectuated by the Company. 
However, for the Plan to be approved, each matter in the Plan
must be approved. THE FAILURE TO APPROVE EACH
MATTER CONTAINED IN THE PLAN, AND THEREFORE
THE PLAN, COULD HAVE A MATERIAL ADVERSE
EFFECT ON THE BUSINESS AND FINANCIAL
CONDITION OF THE COMPANY.

        On August 31, 1998, the Board of Directors of the
Company unanimously approved the Plan.  The Plan is now
being submitted for approval by the Company's stockholders.

        APPROVAL OF A MATTER REQUIRES A "FOR"
VOTE ON THE ACCOMPANYING PROXY.  IF NO
CHOICE IS SPECIFIED IN THE ACCOMPANYING
PROXY, THE PROXY WILL BE VOTED "FOR" THE
MATTER.  A VOTE TO "ABSTAIN" WITH RESPECT TO
A MATTER WILL HAVE THE SAME EFFECT AS A
VOTE "AGAINST" THE MATTER.

              PROPOSAL TO AMEND THE CERTIFICATE OF
INCORPORATION
                TO EFFECT THE REVERSE STOCK SPLIT

Reason for Submission to Stockholders

        ThisIncrease Proposal is being submitted to stockholders to
comply with the terms of the Stock Purchase Agreement and to
satisfy the requirements of the Delaware General Corporation
Law.  The Proposal is one of the matters contained in the Plan
of Recapitalization and Financing (the "Plan") which, pursuant
to the Stock Purchase Agreement, is to be adopted by the
Company and submitted to the Company's stockholders for their
approval.  The failure of the Company's stockholders to
approve this Proposal would constitute a failure to approve
the Plan and could have a material adverse effect on the
business and financial condition of the Company.  See
"Background."

Reasons for the Reverse Stock Split

        The principal reasons to effectuate the Reverse Stock
Split are to increase the number of authorized but unissued
shares of Common Stock, to reduce the number of shares of
Common Stock that are outstanding, and to increase the price per
share of the Common Stock.

        The Company currently is authorized to issue 50,000,000
shares of Common Stock, of which 33,454,302 shares of
Common Stock are issued and outstanding.  There also are
outstanding 128 shares of Series E Preferred Stock and 128
Series E Warrants which are convertible/exercisable into
1,280,000 shares of Common Stock and 640,000 shares of
Common Stock, respectively, and other options and warrants to
purchase 2,096,400 shares of Common Stock.  In addition, in
accordance with the Stock Purchase Agreement, the Company (i)
is required to issue to ValorInvest an additional 256 shares of
Series E Preferred Stock, convertible into 2,560,000 shares of
Common Stock, and Series E Warrants to purchase 1,280,000
shares of Common Stock, and (ii) has granted to management,
others who have provided services to the Company, and
directors an aggregate of 19,155,000 stock options/warrants (pre-
Reverse Stock Split) to appropriately incentivize and/or
compensate them, in each case subject to the approval of the
Plan by the Company's stockholders. Thus, the Company may
be required to issue a number of shares of Common Stock,
which, together with the Company's issued and outstanding
shares of Common Stock, would exceed its current authorized
capital of 50,000,000 shares of Common Stock.  Lastly, there
currently is an insufficient number of authorized but unissued
shares of Common Stock available to allow the Company to
complete the contemplated Public Offering.

        The Company contemplates that the Reverse Stock Split
will be a minimum of one-for-ten (with the final determination
to be based upon the price of the Common Stock at the time of
the Reverse Stock Split and negotiations with the Underwriter,
if any).  After a one-for-ten Reverse Stock Split, there would be
outstanding approximately 3,345,430 shares of Common Stock,
Series E Preferred Stock convertible into 128,000 shares of
Common Stock, Series E Warrants to purchase 64,000 shares of
Common Stock, other options and warrants to purchase
2,125,140 shares of Common Stock (assuming ratification and
approval of the Stock Option/Warrant Grant), and a contractual
commitment to issue to ValorInvest additional Series E Preferred
Stock and Series E Warrants convertible/exercisable into an
aggregate of 384,000 shares of Common Stock, for an aggregate
of approximately 6,046,570 shares of Common Stock issued and
outstanding or required to be reserved for issuance.  Therefore,
the Reverse Stock Split will enable the Company to issue shares
of Common Stock pursuant to the conversion of outstanding and
contracted for shares of Series E Convertible Preferred Stock and
the exercise of outstanding warrants and options, and to
consummate a Public Offering.

        The Company also believes that the higher share price
which may result from the Reverse Stock Split will help to
generate interest in the Company among investors, thereby
facilitating future financings.  In addition, the Company
anticipates, but there can be no assurance, that the Reverse Stock
Split will enable the Common Stock to maintain its listing on the
NASDAQ Stock Market, for which a minimum $1.00 bid price
is required.  There can be no assurance, however, that a higher
share price will have such effect or that any financings will be
consummated in the future. 

Fractional Shares

        No fractional shares of Common Stock or scrip
representing fractional shares of Common Stock will be issued
in connection with the Reverse Stock Split.  In lieu of issuing
fractional shares, each fractional share will be rounded up to the
next highest whole share of Common Stock.

Effects of the Reverse Stock Split

        Upon the effectiveness of the Reverse Stock Split, the
number of shares owned by each holder of Common Stock shall
be reduced by the ratio of a minimum of 5 to 1 and a maximum
of 16 to 1, so that each such stockholder will thereafter own one
share of Common Stock for every 5 or 6 or 7 or 8 or 9 or 10 or
11 or 12 or 13 or 14 or 15 or 16 shares of Common Stock he or
she owned immediately prior to the Reverse Stock Split.

        It is contemplated that the Reverse Stock Split will be a
minimum of one-for-10 (with the final determination to be based
upon the price of the Common Stock at the time of the Reverse
Stock Split and negotiations with the Underwriter, if any). 
Assuming a one-for-10 Reverse Stock Split, the principal effect
of the Reverse Stock Split will be that (i) the number of shares
of Common Stock issued and outstanding will be reduced from
33,454,302 shares to approximately 3,345,430 shares, (ii) all
outstanding shares of Series E Preferred Stock entitling holders
thereof to receive, upon conversion, shares of Common Stock
will enable such holders to receive, upon conversion thereof,
1/10th of the number of shares of Common Stock which such
holders would have received upon conversion thereof
immediately preceding the Reverse Stock Split, (iii) all
outstanding options and warrants entitling the holders thereof to
purchase shares of Common Stock will enable such holders to
purchase, upon exercise of their options and warrants, 1/10 of
the number of shares of Common Stock which such holders
would have been able to purchase upon exercise of their options
or warrants immediately preceding the Reverse Stock Split at the
same aggregate price required to be paid therefor upon exercise
thereof immediately preceding the Reverse Stock Split, and (iv)
the number of shares included in the Company's 1998 Stock
Option Plan will be reduced to 1/10th of the number of shares
currently included in such Stock Option Plan.  The Reverse
Stock Split will not alter the percentage ownership interest in the
Company of any stockholder, except to the extent that the
Reverse Stock Split results in a stockholder of the Company
owning a fractional share (see "Reverse Stock Split - Fractional
Shares").  Voting and other rights accompanying the Common
Stock will not be altered.

        Pursuant to the Reverse Stock Split, the par value of the
Common Stock will remain $0.001 per share.  As a result, on
the effective date of the Reverse Stock Split, the stated capital on
the Company's balance sheet attributable to the Common Stock
will be reduced to 1/10th of its present amount (assuming a one-
for-ten Reverse Stock Split), and the additional paid-in capital
account shall be credited with the amount by which the stated
capital is reduced.

Exchange of Shares

        The Reverse Stock Split will be effective at the close of
business on the date of filing of the appropriate certificate of
amendment to the Charter with the Secretary of State of the State
of Delaware, unless the Company specifies otherwise.  The
record date for the Reverse Stock Split will be the effective date
of the amendment to the Charter (the "Record Date").  On or
about the Record Date, notice of the Reverse Stock Split (the
"Split Notice") will be mailed to each stockholder of record at
the most recent address of such stockholder appearing on the
Company's records.  The Split Notice shall be accompanied by
a Letter of Transmittal and shall request that each stockholder
surrender his or her existing stock certificate(s) (the "Old
Certificate") evidencing ownership of the pre-Reverse Stock Split
Common Stock (the "Old Common Stock"), together with the
Letter of Transmittal, to American Stock Transfer and Trust
Company to be exchanged for a new stock certificate(s)
evidencing ownership of the number of shares of Common Stock
resulting from the Reverse Stock Split (the "New Common
Stock").  From and after the Record Date, all Old Certificates
will be deemed to represent only that number of shares of New
Common Stock resulting from the Reverse Stock Split.

Federal Income Tax Consequences

        The Company believes that the federal income tax
consequences of the Reverse Stock Split will be as follows:

        (i)             Except as explained in (v) below, no
                        income gain or loss will be recognized
                        by stockholders on the surrender of their
                        Old Common Stock or the receipt of
                        their New Common Stock.

        (ii)            Except as explained in (v) below, the
                        tax basis of the New Common Stock
                        will equal the tax basis of the Old
                        Common Stock exchanged therefor.

        (iii)   Except as explained in (v) below, the holding
                period of the New Common Stock will include
                the holding period of the Old Common Stock if
                such shares were held as capital assets.

        (iv)    The conversion of the Old Common Stock into
                the New Common Stock will produce no taxable
                income or gain or loss to the Company.

        (v)             The federal income tax treatment of the
                        receipt of the additional fractional
                        interest by a stockholder is not clear and
                        may result in tax liability not material in
                        amount in view of the low value of such
                        fractional interest.

        The foregoing summary represents the Company's
opinion only and is based on the existing provisions of the
Internal Revenue Code of 1986, as amended, and existing
administrative interpretations thereof, any of which may be
revised retroactively.  The Company's opinion is not binding
upon the Internal Revenue Service or the courts, and there can
be no assurance that the Internal Revenue Service or the courts
would accept the positions expressed above.

        The state and local tax consequences of the Reverse
Stock Split may vary significantly as to each stockholder,
depending upon the state in which he/she resides.  Stockholders
are urged to consult their own tax advisors with respect to the
federal, state, and local tax consequences of the Reverse Stock
Split.

No Right of Appraisal

        Under the Delaware General Corporation Law,
dissenting stockholders are not entitled to appraisal rights with
respect to the Company's proposed amendment to the Charter to
effect the Reverse Stock Split, and the Company will not provide
stockholders with any such right.

Voting Requirement

        Approval of the Proposal for the Reverse Stock Split requires the affirmative vote of the
holders of stock representing a majority of the votes entitled to be cast at the
Meeting. Approval of the Plan Increase Proposal and the ratification of the
independent auditors requires the affirmative vote of the holders of stock
representing a majority of shares present in person or represented by proxy at
the Meeting and entitled to vote thereon.

All votes will be tabulated by the inspector(s) of election appointed for the
Meeting, who will separately tabulate affirmative and negative votes,
abstentions and broker non-votes. Abstentions and broker non-votes shall each be
included as shares present and voting for the purpose of determining whether a
quorum is present at the Meeting. Abstentions will be counted toward the
tabulation of votes cast on the Proposals and will have the same effect as
negative votes. Broker non-votes are not counted in determining whether a
Proposal has been approved.

                                       2



PROPOSAL NO. 1 - ELECTION OF DIRECTORS
- --------------------------------------

NOMINEES

Four persons, all of whom are members of the present Board of Directors, are
nominees for election at the Annual Meeting to hold office until the next annual
meeting and until their respective successors are elected and qualified. Unless
authority to vote for any director is withheld in a proxy, it is intended that
each proxy will be voted for the four nominees named below.

It is expected that all nominees will be able and willing to serve as directors.
However, in the event that any nominee is unable or declines to serve as a
director at the time of the Annual Meeting, the proxies will be voted for any
nominee who shall be designated by the present Board of Directors to fill the
vacancy. The Board of Directors recommendshas no reason to believe that any of the persons
named will be unable or unwilling to serve as director if elected.

REASON FOR SUBMISSION TO STOCKHOLDERS

This Proposal is being submitted to stockholders to satisfy the requirements of
the Delaware General Corporation Law.

REQUIRED VOTE

Approval of the nominees for election to the Board of Directors will require the
affirmative vote of the holders of stock representing a plurality of the votes
present at the Annual Meeting in person or by proxy and entitled to vote.

THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE FOR THE ELECTION OF
ALL NOMINEES LISTED TO THE BOARD OF DIRECTORS.

NOMINEES FOR ELECTION TO THE BOARD OF DIRECTORS

       Name                           Age      Present Office or Position
       ----                           ---      --------------------------

       John G. Baust, Ph.D.           62       Director, Chief Executive Officer

       Howard S. Breslow              65       Director, Secretary

       Roderick de Greef              43       Director

       Thomas Girschweiler            47       Director


The following information is submitted concerning the nominees named for
election as directors based upon information received by the Company from such
persons.

                                       3



John G. Baust, Ph.D., has been the President and Chief Executive Officer of the
Company since July 2002. Previously he was Senior Vice President of Cryomedical
Sciences, Inc. ("CMSI"), the Company's predecessor, since January 1995, Chief
Scientific Officer since August 1993, Vice President, Research and Development
from July 1990 to January 1995, and a consultant from April 1990 to July 1990.
Dr. Baust became a director of CMSI on October 13, 2000. Since 1987, Dr. Baust
has also been a Professor and the Director of the Center for Cryobiological
Research at the State University of New York at Binghamton, and since July 1994,
Dr. Baust has also been Adjunct Professor of Surgery, Medical College of
Pennsylvania. From 1984 to 1987, he was a Professor at, and the Director of, the
Institute of Low Temperature Biology at the University of Houston.

Howard S. Breslow has served as a director of the Company since July 1988. He
has been a practicing attorney in New York City for 40 years and is a member of
the law firm of Breslow & Walker, LLP, New York, New York, which firm serves as
general counsel to the Company. Mr. Breslow currently serves as a director of
Excel Technology, Inc., a publicly-held company engaged in the manufacture and
marketing of photonics-based solutions, consisting of laser systems and
electro-optical components, primarily for industrial and scientific
applications, and Lucille Farms, Inc., a company engaged in the manufacture and
marketing of dairy products.

Roderick de Greef has served as a director of the Company since June 19, 2000.
From March 2001 to present, Mr. de Greef has served as Executive Vice President,
Chief Financial Officer and Secretary of Cardiac Sciences, Inc., a public
company traded on NASDAQ, under the ticker "DFIB". Since 1995 Mr. de Greef has
provided corporate finance advisory services to a number of early stage
companies, including the Company, where he was instrumental in securing the
Company's equity capital beginning in June 2000, and advising on merger and
acquisition activity. From 1989 to 1995, Mr. de Greef was Vice President and
Chief Financial Officer of BioAnalogics, Inc. and International BioAnalogics,
Inc., publicly held, development stage medical technology companies located in
Portland, Oregon. From 1986 to 1989, Mr. de Greef was Controller and then Chief
Financial Officer of Brentwood Instruments, Inc., a publicly held cardiology
products distribution company based in Torrance, California. Mr. de Greef has a
B.A. in Economics and International Relations from California State University
at San Francisco and an M.BA. from the University of Oregon.

Thomas Girschweiler joined the Board in 2003. Mr. Girschweiler has been engaged
in corporate financing activities on his own behalf since 1996. From 1981 to
1996 he was an investment banker with Union Bank of Switzerland. Thomas
Girschweiler was graduated at the Swiss Banking School.

DIRECTOR COMPENSATION

The Company has not compensated its directors for their services in such
capacity, except that on May 12, 2005, each of the directors received a ten-year
fully vested non-incentive stock option to purchase 250,000 shares of the
Company's common stock at $0.08 per share.

                                       4



BOARD MEETINGS

The Board of Directors held meetings or acted by unanimous consent on fourteen
(14) occasions during the twelve months ended December 31, 2004. Meetings were
attended by all directors. Although the Company does not have a formal policy
regarding attendance by the Board of Directors at the Company's Annual Meeting
of Stockholders, it strongly encourages directors to attend. Because of
financial constraints, the Company did not hold an Annual Meeting of
Stockholders last year.

BOARD COMMITTEES

AUDIT COMMITTEE. The Board of Directors does not have an audit committee or an
audit committee financial expert. The Company does believe, based on its current
operations, that the stockholders vote FOR the proposed amendmentfailure to have such a committee or expert is material to
the Charterintegrity of the financial statements of the Company.

COMPENSATION COMMITTEE. The Board of Directors does not have a compensation
committee. Management compensation for fiscal year 2004 was determined by the
non-employee members of the Board of Directors.

NOMINATING COMMITTEE. The Board of Directors has no standing nominating
committee. The Company believes that obtaining input from all of its directors
in connection with Board nominations enhances the nomination process. The
Company currently does not have a charter with regard to effect the Reversenomination process.
The nominations of the directors standing for election or re-election at the
Meeting were unanimously recommended for selection by the independent directors
(as defined by NASDAQ rules), and were unanimously approved by the Board of
Directors.

The Company does not have a formal policy concerning stockholder recommendations
of nominees to the Board of Directors. The need for such a policy has not arisen
since, to date, the Company has not received any recommendations from
stockholders requesting that the Board of Directors consider a candidate for
inclusion among the Board's slate of nominees in the Company's proxy statement.
The absence of such a policy does not mean, however, that a recommendation would
not have been considered had one been received. The Company will consider
director candidates recommended by stockholders. Any stockholder desiring to
make such a recommendation should send the recommendation, in writing, to the
Corporate Secretary at the address of the Company set forth on the first page of
this Proxy Statement, no later than the date by which stockholder proposals for
action must be submitted. The recommendation should include the recommended
candidate's biographical data, and should be accompanied by the candidate's
written consent to nomination and to serving as a director, if elected.

The Company's goal is to assemble a Board of Directors that brings to the
Company a variety of perspectives and skills derived from business and
professional experience. The Company does not have any formal rules or policies
regarding minimum qualifications for nominees, but expects that its candidates
be of the highest ethical character, share the values of the Company, have
reputations, both personal and professional, consistent with the image and
reputation of the

                                       5



Company, be highly accomplished in their respective field, and possess the
relevant expertise and experience necessary to assist the Board of Directors and
the Company to increase stockholder value.

The Board of Directors identifies nominees by first evaluating the current
members of the Board of Directors willing to continue in service. Current
members of the Board with skills and experience that are relevant to the
Company's business and who are willing to continue in service are considered for
re-nomination, balancing the value of continuity of service by existing members
of the Board with that of obtaining a new perspective. If any member of the
Board does not wish to continue in service or if the Board of Directors decides
not to re-nominate a member for re-election, the Board of Directors will seek to
identify nominees that possess the characteristics outlined above. Current
members of the Board of Directors are polled for suggestions. Research also may
be performed to identify qualified individuals. To date, the Company has not
engaged third parties to identify, evaluate, or assist in identifying potential
nominees, although the Company reserves the right in the future to retain a
third party search firm, if necessary.

In evaluating director nominees, the Board of Directors may consider the
following factors:

    o   the appropriate size and the diversity of the Company's Board of
        Directors;

    o   the needs of the Company with respect to the particular talents and
        experience of its directors;

    o   the knowledge, skills and experience of nominees, including experience
        in technology, business, or finance, in light of prevailing business
        conditions and the knowledge, skills and experience already possessed by
        other members of the Board;

    o   familiarity with national and international business matters;

    o   experience with accounting rules and practices; and

    o   the need to satisfy governance and other standards set by the SEC.

The Board of Directors may also consider such other factors as it may deem to be
in the best interests of the Company and its stockholders.

COMMUNICATING WITH DIRECTORS

Stockholders may contact any of our directors or our Board of Directors as a
group by writing to them c/o BioLife Solutions, Inc., 171 Front Street, Owego,
NY 13827, Att: Dr. John G. Baust. All communications will be received, processed
and forwarded to the directors by the Corporate Secretary. You will receive a
written acknowledgement from the Corporate Secretary upon receipt of your
communication if you include a return address.

                                       6



EXECUTIVE OFFICERS OF THE REGISTRANT

The executive officers of the Company are as follows:

       Name                          Age      Present Office or Position
       ----                          ---      --------------------------

       John G. Baust, Ph.D.          62       Chief Executive Officer, President


Officers are appointed by, and hold office at the pleasure of, the Board of
Directors. Officers serve at the discretion of the Board of Directors and are
elected at the annual meeting of the Board of Directors.

                                       7



EXECUTIVE COMPENSATION

The following table sets forth certain information concerning the compensation
paid by the Company to its Chief Executive Officer and to each of its executive
officers (other than the Chief Executive Officer) who received salary and bonus
payments in excess of $100,000 during the fiscal year ended December 31, 2004
(collectively the "Named Executive Officers").

Annual Compensation Long Term Compensation -------------------------------------- -------------------------------------------------- Awards Payouts ----------------------- ------------------------ Other Annual Restricted Name and Principal Fiscal Salary Bonus Compensation Stock Options/ LTIP All Other Positions Year ($) ($) ($) Award(s) SARs (#) Payouts Compensation - ------------------------ --------- --------- --------- -------------- --------- ---------- -------- ------------- John G. Baust, Ph.D 2004 240,000(1) -- -- -- -- -- -- Chief Executive Office,r 2003 240,000(2) -- 7,490 (3) -- -- -- -- President, and 2002 202,369 50,000 3,600 (3) -- 1,000,000 -- -- Director Alan Rich 2004 174,587(4) -- 7,200(3) -- -- -- -- VP Sales & Marketing 2003 150,000(5) -- -- -- 100,000 -- -- 2002 15,000 -- -- -- -- -- --
(1) Consists of $176,490 paid compensation and $63,510 accrued salary paid in 2005. (2) Consists of $170,654 paid compensation, $53,125 paid in 2.125 units of Series G Preferred Stock, Split.and $16,221 accrued salary paid in 2004. (3) Represents auto allowance. (4) Consists of $150,000 paid compensation, $20,248 paid commissions, and $4,339 accrued commissions paid in 2005. (5) Consists of $103,846 paid compensation, $12,500 paid in 1.0 units of Series G Preferred Stock, and $33,654 accrued salary paid in 2004. OPTION/SAR GRANTS IN YEAR-ENDED DECEMBER 31, 2004 In 2004, the Company issued no options to purchase shares of Common Stock to its Named Executive Officers. 8 AGGREGATED OPTION/SAR EXERCISES DURING THE 2004 FISCAL YEAR AND THE 2004 FISCAL YEAR OPTION/SAR VALUES The following table provides information related to options exercised by each of the Named Executive Officers during the 2004 fiscal year and the number and value of options held at December 31, 2004. The Company does not have any outstanding stock appreciation rights. None of the options were in the money at December 31, 2004.
Number of Securities Value of Unexercised Underlying Unexercised in the money Options/SAR at Fiscal Options/SAR at Fiscal Year End (#) Year End ($)(1) -------------------------- --------------------------- Shares Acquired Value Name On Exercise(#) Realized($) Exercisable Unexercisable Exercisable Unexercisable - ---------- --------------- ----------- ----------- ------------- ----------- ------------- John G. Baust, Ph.D. -- -- 1,542,000 1,000,000 -- -- Alan F. Rich -- -- -- -- -- --
- ---------------------------------------- (1) The closing price for the Common Stock as reported on the OTC Bulletin Board on December 31, 2004 was $0.09. Value is calculated on the basis of the difference between the option exercise price and $0.09 multiplied by the number of shares of Common Stock underlying the option. (2) Mr. Rich's employment relationship with the Company ended in February 2005. EMPLOYMENT AGREEMENTS The Company has an employment agreement with its President and Chief Executive Officer, dated July 1, 2002, which was to expire on June 30, 2004, but which was automatically renewed for a one-year term. The agreement provides for a salary of $20,000 per month and an incentive bonus based on certain milestones, as determined by the Board of Directors. The officer also received a $50,000 signing bonus in 2002 and ten-year incentive stock options to purchase 1,000,000 shares of Common Stock, which options vest ratably over five years on the anniversary date of the grant. The agreement also provides an automobile allowance of $600 per month. The Company had an employment agreement with its Vice President, Sales and Marketing which expired on October 31, 2004. The agreement provided for a salary of $12,500 per month, an incentive bonus based on certain milestones, as determined by the Board of Directors, ten-year incentive stock options to purchase 400,000 shares of Common Stock vesting ratably over four years on the anniversary date of the grant, and an automobile allowance of $600 per month. Mr. Rich's employment relationship with the Company ended in February 2005. Every officer of the Company has executed a Proprietary Information and Inventions Agreement pursuant to which each agreed, among other things, to keep the Company's information confidential and assigned all inventions to the Company, except for certain personal inventions not related to the Company's work, whether existing or later developed. 9 COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION Management compensation for fiscal year 2004 was determined by the non-employee members of the Board. There were no compensation committee interlocks. CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS Until 2004, the Company conducted its internal research through Small Business Innovative Research ("SBIR") grants awarded by the National Institutes of Health. In 2004, the Company elected to not continue to directly engage in the SBIR grant program. Accordingly, the Company entered into a Research Agreement with Cell Preservation Services, Inc. ("CPSI") to outsource to CPSI all BioLife research currently funded through SBIR grants. CPSI is owned by Dr. John M. Baust, a recognized expert in cell preservation, a former employee of BioLife and the son of John G. Baust, the CEO of BioLife. Robert Van Buskirk, formerly Vice President, Business Development of BioLife and the person primarily responsible for processing applications for SBIR grants for BioLife, also has left the employ of BioLife and joined CPSI. The Research Agreement, which was negotiated on an arms length basis and designed to comply with the rules and regulations applicable to the performance of research with respect to SBIR grants, establishes a format pursuant to which CPSI will (a) take over the processing of existing applications for SBIR grants applied for by BioLife ("Current Projects"), (b) apply for additional SBIR grants for future research projects ("Future Projects"), (c) perform a substantial portion of the principal work to be done, in terms of (i) time spent, and (ii) research, in connection with Current Projects and Future Projects (the "Research"), and (d) utilize BioLife personnel as consultants with respect to such Research. In conjunction therewith BioLife has granted to CPSI a non-exclusive, royalty free license (with no right to sublicense) to use BioLife's technology solely for the purpose of conducting the research in connection with the Current Projects and Future Projects. Pursuant to the Research Contract, (x) BioLife will, among other matters, provide CPSI with (i) suitable facilities in which to conduct the Research, including basic research equipment and office equipment ("Facilities"), and (ii) management services ("Management Services"), and (y) CPSI will (i) accept assignment of Current Projects, (ii) be responsible for conducting Research with respect to Current Projects and Future Projects, (iii) as mutually agreed to by the parties and within the confines of the rules and regulations applicable to the performance of Research with respect to SBIR grants, utilize BioLife's personnel as consultants, (iv) provide suitable experienced personnel, including, without limitation, a principal investigator/program director, to conduct the Research, (v) comply with all federal laws, rules and regulations applicable to SBIR grants and file all necessary forms and reports with the federal agency awarding the SBIR grants, and (vi) utilize the Facilities and Management Services and pay BioLife fees with respect thereto. BioLife is to own all right, title and interest in and to any technology, inventions, designs, ideas, and the like (whether or not patentable) that emanates from the Current Projects, Future Projects and Research. Howard S. Breslow, a director of the Company, is a member of Breslow & Walker, LLP, general 10 counsel to the Company. Mr. Breslow currently owns 53,600 shares of Common Stock of the Company and directly or indirectly owns options and warrants to purchase an aggregate of 2,477,910 additional shares. The Company incurred $80,118 in legal fees during the year ended December 31, 2004 for services provided by Breslow & Walker, LLP. At December 31, 2004 accounts payable includes $28,027 due to Breslow & Walker, LLP. Thomas Girschweiler, a director of the Company, loaned the Company, in the form of notes, $250,000, $100,000 and $100,000 in March 2002, March 2003 and May 2003, respectively. The notes accrued interest at the rate of 10% per annum. On March 1, 2004, the Company paid Mr. Girschweiler $515,418, including principal and accrued interest, in satisfaction of the outstanding notes. REPORT OF THE BOARD OF DIRECTORS ON EXECUTIVE COMPENSATION COMPENSATION GUIDELINES The Company is engaged in a highly competitive industry and must attain high levels of quality and safety in the formulation and production of its products. To succeed, the Company believes that it must offer executive compensation that reflects competitive pay practices of other companies and job responsibility, and enables the Company to attract, retain, and reward qualified, experienced executives. The Company also believes that any competitive pay package should be structured, in part, to align management's interests with the success of the Company by making a portion of compensation dependent on operating achievements and, to a lesser extent, on stock performance. The non-employee members of the Board of Directors have determined that these objectives are best met by offering the Company's executive officers competitive base salaries, stock options that vest over time, and, where appropriate, bonuses based on the achievement of milestones, as determined by the Board of Directors. CHIEF EXECUTIVE OFFICER COMPENSATION Based on the criteria described above, the non-employee members of the Board of Directors ratified the automatic renewal provision of Dr. Baust's employment contract in 2004. In making the determination, the non-employee directors considered several factors including the Company's revenues, losses, and cash-flow and future business prospects. Dr. Baust did not receive a bonus in 2004. Howard S. Breslow Roderick deGreef Thomas Girschweiler 11 BENEFICIAL OWNERSHIP OF THE COMPANY'S SECURITIES The following table sets forth, as of August 15, 2005, certain information regarding the beneficial ownership of Common Stock and Series F Preferred Stock and Series G Preferred Stock by (i) each stockholder known by the Company to be the beneficial owner of more than 5% of the outstanding shares thereof; (ii) each director of the Company; (iii) each Named Executive Officer of the Company; and (iv) all of the Company's current directors and executive officers as a group.
Name and Address Common Stock Series F Preferred Series G Preferred of Beneficial Owner (% of class) (1) (% of class) (% of class) - -------------------------------------------- --------------------- -------------------- --------------------- John G. Baust (Director, Executive Officer) c/o BioLife Solutions, Inc. 171 Front Street 3,640,525 (22.7%)(2) -- 2.125 (3.9%) Owego, NY 13827 Howard S. Breslow, Esq. (Director) c/o Breslow & Walker, LLP 767 Third Avenue 2,531,510 (17.0%)(3) -- - New York, NY 10017 Roderick de Greef (Director) c/o BioLife Solutions, Inc. 171 Front Street 4,514,699 (27.4%)(4) 1,000 (8.3%) 4.0 (7.3%) Owego, NY 13827 Walter Villiger Hurdnerstrasse 10 P.O. Box 1474 17,072,314 (58.7%)(5) 5,000 (41.7%) 18.0 (32.7%) CH-8649 Hurden, Switzerland Thomas Girschweiler (Director) Wissmannstrasse 15 12,854,278 (52.0%)(6) 3,450 (28.8%) 10.0 (18.1%) 8057 Zurich, Switzerland Karl-Heinz Illenseer Wissmannstrasse 15 3,910,714 (24.0%)(7) -- 6.0 (10.9%) 8057 Zurich, Switzerland Clariden Bank Claridenstrasse 26 Postfach 5080 2,520,513 (17.8%)(8) 2,000 (16.7%) -- CH-8022 Zurich, Switzerland Richard Molinsky c/o BioLife Solutions, Inc. 171 Front Street 2,583,333 (17.2%)(9) -- 4.0 (7.3%) Owego, NY 13827 Francois Illenseer Wissmannstrasse 15 2,607,143 (17.4%)(10) -- 4.0 (7.3%) 8057 Zurich, Switzerland Charlotte Illenseer Wissmannstrasse 15 2,607,143 (17.4%)(11) -- 4.0 (7.3%) 8057 Zurich, Switzerland Robert Van Buskirk 1,095,935 (8.1%)(12) -- 1 (1.8%) c/o CPSI, 2 Court Street Owego, New York 13827
12
Name and Address Common Stock Series F Preferred Series G Preferred of Beneficial Owner (% of class) (1) (% of class) (% of class) - -------------------------------------------- --------------------- -------------------- --------------------- John M. Baust 1,085,340(8.0%)(13) -- 1 (1.8%) c/o CPSI, 2 Court Street Owego, New York 13827 All officers and directors as a group (four persons) 23,541,012 (67.9%) 4,450 (37.1%) 16.125 (29.3%)
- ---------- (1) Shares of Common Stock subject to options and warrants currently exercisable or exercisable within 60 days of July 31, 2005 are deemed outstanding for computing the number of shares and the percentage of the outstanding shares held by a person holding such options or warrants, but are not deemed outstanding for computing the percentage of any other person. Except as indicated by footnote, and subject to community property laws where applicable, the Company believes that the persons named in the table have sole voting and investment power with respect to all shares shown as beneficially owned by them. (2) Includes 1,942,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 664,063 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 990,618 shares of Common Stock issuable upon the exercise of outstanding warrants, and 43,844 shares of Common Stock, 39,844 of which were earned as dividend on Preferred Stock. (3) Includes 399,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 2,078,910 shares of Common Stock issuable upon the exercise of outstanding warrants owned of record by Breslow & Walker, LLP (1,358,910) and B & W Investments (720,000), both of which are entities in which Mr. Breslow is a partner, and 53,600 common shares. (4) Includes 250,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 400,000 shares of Common Stock issuable upon the conversion of Series F Preferred Stock, 1,250,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 1,814,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 800,699 shares of Common Stock, 367,399 of which were earned as dividend on Preferred Stock. (5) Includes 2,000,000 shares of Common Stock issuable upon the conversion of Series F Preferred Stock, 5,625,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 7,375,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 2,072,314 shares of Common Stock, 1,672,314 of which were earned as dividend on Preferred Stock. (6) Includes 250,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 1,380,000 shares of Common Stock issuable upon the conversion of Series F Preferred Stock, 3,125,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 6,455,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 1,644,278 shares of Common Stock, 1,106,218 of which were earned as dividend on Preferred Stock. (7) Includes 1,875,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 1,875,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 160,714 shares of Common Stock earned as dividend on Preferred Stock. (8) Includes 800,000 shares of Common Stock, 800,000 shares of Common Stock issuable upon the conversion of Series F Preferred Stock, 400,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 520,513 shares of Common Stock earned as dividend on Preferred Stock. (9) Includes 1,250,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 1,250,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 83,333 shares of Common Stock earned as dividend on Preferred Stock. (10) Includes 1,250,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 1,250,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 107,143 shares of Common Stock earned as dividend on Preferred Stock. (11) Includes 1,250,000 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 1,250,000 shares of Common Stock issuable upon the exercise of outstanding warrants, and 107,143 shares of Common Stock earned as dividend on Preferred Stock. (12) Includes 275,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 312,500 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 489,685 shares of Common Stock issuable upon the exercise of outstanding warrants, and 18,750 shares of Common Stock earned as dividend on Preferred Stock. (13) Includes 250,000 shares of Common Stock issuable upon the exercise of outstanding stock options under the Company's 1988 and 1998 Stock Option Plans, 312,500 shares of Common Stock issuable upon the conversion of Series G Preferred Stock, 504,090 shares of Common Stock issuable upon the exercise of outstanding warrants, and 18,750 shares of Common Stock earned as dividend on Preferred Stock. 13 COMPARISON OF CUMULATIVE TOTAL STOCKHOLDER RETURN The following chart compares the percentage change in the cumulative total stockholder return on the Common Stock during the period from December 31, 1999 through the year ended December 31, 2004 with the cumulative total return on the NASDAQ Composite Index and the Company Peer Group. The comparison assumes $100 was invested in the Common Stock on December 31, 1999, and in each of the stocks included in the NASDAQ Composite Index and the Company Peer Group. COMPARE 5-YEAR CUMULATIVE TOTAL RETURN AMONG BIOLIFE SOLUTIONS, INC., NASDAQ MARKET INDEX AND PEER GROUP INDEX [GRAPHIC OMITTED] ASSUMES $100 INVESTED ON DEC. 31, 1999 ASSUMES DIVIDEND REINVESTED FISCAL YEAR ENDING DEC. 31, 2004
- -------------------------------------------------------------------------------------------------------------- ---------------------------- FISCAL YEAR ENDING --------------------------- COMPANY/INDEX/MARKET 12/31/1999 12/29/2000 12/31/2001 12/31/2002 12/31/2003 12/31/2004 BIOLIFE SOLUTIONS, INC 100.00 312.50 131.25 75.00 68.75 56.25 CUSTOMER SELECTED STOCK LIST 100.00 177.16 201.11 142.50 212.07 227.24 NASDAQ MARKET INDEX 100.00 62.85 50.10 34.95 52.55 56.97 - --------------------------------------------------------------------------------------------------------------
14 PROPOSAL TONO. 2 - AMEND THE CERTIFICATE OF INCORPORATION TO EFFECT THE COMMON STOCK REDUCTION Reason for SubmissionINCREASE REASON FOR SUBMISSION TO STOCKHOLDERS The Board of Directors unanimously adopted a resolution proposing that Article Four of the Company's Certificate of Incorporation be amended to Stockholdersincrease the number of shares of Common Stock that the Company is authorized to issue from 25,000,000 to 100,000,000 shares. This Proposalproposal is being submitted to stockholders to comply with the terms of the Stock Purchase Agreement and to satisfy the requirements of the Delaware General Corporation Law. The Proposal is one of the matters contained in the Plan of Recapitalization and Financing (the "Plan") which, pursuant to the Stock Purchase Agreement, is to be adopted by the Company and submitted to the Company's stockholders for their approval. The failure of the Company's stockholders to approve this Proposal would constitute a failure to approve the Plan and could have a material adverse effect on the business and financial condition of the Company. See "Background." Reasons for Reducing the Number of Authorized Shares of Common StockREASONS FOR INCREASING THE NUMBER OF AUTHORIZED SHARES OF COMMON STOCK Presently, the Chartercharter authorizes the issuance of 50,000,00025,000,000 shares of Common Stock, of which 33,454,30212,413,209 shares of Common Stock are issued and outstanding. There alsoAlso, there are outstanding (i) shares of Series EF Preferred Stock convertible into 4,800,000 shares of Common Stock, (ii) shares of Series G Preferred Stock convertible into 17,226,563 shares of Common Stock, (iii) warrants and Series E Warrants convertible/options exercisable into 1,280,000an aggregate of 30,777,858 shares of Common Stock, and 640,000(iv) 4,365,432 shares of Common Stock respectively, and other optionsearned as dividends on Preferred Stock. Assuming the conversion/exercise of all outstanding Series F Preferred Stock, Series G Preferred Stock, and warrants to purchase 2,096,400 shares of Common Stock. In addition, in accordance with the Stock Purchase Agreement, the Company (i) is required to issue to ValorInvest an additional 256 shares of Series E Preferred Stock, convertible into 2,560,000 shares of Common Stock, and Series E Warrants to purchase 1,280,000 shares of Common Stock, and (ii) has granted to management, others who have provided services to the Company, and directors an aggregate of 19,155,000 stock options/warrants (pre-Reverse Stock Split) to appropriately incentivize and/or compensate them, in each case subject to the approval of the Plan by the Company's stockholders. Assuming a minimum one-for-ten Reverse Stock Split,options, there would be outstanding a maximum of approximately 3,345,430 shares of Common Stock, Series E Preferred Stock convertible into 128,000 shares of Common Stock, Series E Warrants to purchase 64,000 shares of Common Stock, other options and warrants to purchase 2,125,140 shares of Common Stock (assuming ratification and approval of the Stock Option/Warrant Grant), and a contractual commitment to issue to ValorInvest additional Series E Preferred Stock and Series E Warrants convertible/exercisable into an aggregate of 384,000 shares of Common Stock, for an aggregate of approximately 6,046,57069,583,062 shares of Common Stock issued and outstanding or required to be reserved for issuance. In such case, anoutstanding. Thus, there are not a sufficient number of authorized capital of 50,000,000 shares of Common Stock would be unnecessary. Rather,available for the Board of Directors believes that an authorized capital of 25,000,000 shares of Common Stock would be sufficient to ensure that the Company has enough shares of Common Stock available to meet its outstanding commitments as well as to provide the Company with flexibility in connection with various corporate purposes, including the Public Offering, if any, and possible future financings and acquisitions requiringstock option grants. In connection with the issuance of various securities convertible/exercisable into shares of Common Stock. EffectStock, the Company undertook to amend its certificate of incorporation to increase the Reduction The reductionnumber of authorized shares of Common Stock so as to meet its commitments upon the conversion/exercise of such securities (the "Committed Shares"). EFFECTS OF THE COMMON STOCK INCREASE The Common Stock Increase will not alter the par value of the Common Stock or the rights of stockholders. No RightIt will allow the Company to meet its commitments to those security holders who are entitled to the Committed Shares. To the extent the Company issued shares of Appraisalcommon stock over and above the amount required to satisfy its commitments to current security holders, such issuances would reduce the proportionate interests in the Company held by current stockholders as well as those who receive the Committed Shares. NO RIGHT OF APPRAISAL Under the Delaware General Corporation Law, dissenting stockholders are not entitled to appraisal rights with respect to the Company's proposed amendment to the Charter to effect the Common Stock Reduction,Increase, and the Company will not provide stockholders with any such right. Voting Requirement In accordance with the Charter, approval of the Proposal for the Common Stock Reduction requires the affirmative vote of the holders of stock representing a majority of the votes entitled to be cast at the Meeting. The Board of Directors recommends that the stockholders vote FOR the proposed amendment to the Charter to effect the Common Stock Reduction. PROPOSAL15 METHOD OF EFFECTING THE AMENDMENT TO AMEND THE CERTIFICATE OF INCORPORATION TO EFFECT THE PREFERRED STOCK REDUCTION Reason for Submission to Stockholders This Proposal is being submitted to stockholders to comply with the terms of the Stock Purchase Agreement and to satisfy the requirements of the Delaware General Corporation Law. The Proposal is one of the matters contained in the Plan of Recapitalization and Financing (the "Plan") which, pursuant to the Stock Purchase Agreement, is to be adopted by the Company and submitted to the Company's stockholders for their approval. The failure of the Company's stockholders to approve this Proposal would constitute a failure to approve the Plan and could have a material adverse effect on the business and financial condition of the Company. See "Background." Reasons for Reducing the Number of Authorized Shares of Preferred Stock Presently the Charter authorizes the issuance of 9,378,800 shares of Preferred Stock, of which 128 shares, designated as Series E Convertible Preferred Stock, are issued and outstanding. Under such circumstances, authorized capital of 9,378,800 shares of Preferred Stock is unnecessary. Rather, the Board of Directors believes that an authorized capital of 1,000,000 shares of Preferred Stock would be sufficient to ensure that the Company has enough shares of Preferred Stock available to meet its outstanding commitments as well as to provide the Company with flexibility in connection with various corporate purposes, including the Public Offering, if any, and possible future financings and acquisitions requiring the issuance of Preferred Stock. Effect of the Reduction The reduction of authorized shares of Preferred Stock will not alter the par value of the Preferred Stock or the rights of stockholders. No Right of Appraisal Under the Delaware General Corporation Law, dissenting stockholders are not entitle to appraisal rights with respect to the Company's proposed amendment to the Charter to effect the Preferred Stock Reduction, and the Company will not provide stockholders with any such right. Voting Requirement In accordance with the Charter, approval of the Proposal for the Preferred Stock Reduction requires the affirmative vote of the holders of stock representing a majority of the votes entitled to be cast at the Meeting. The Board of Directors recommends that the stockholders vote FOR the proposed amendment to the Charter to effect the Preferred Stock Reduction. Method of Effecting the Charter Amendments The Reverse Stock Split, the Common Stock Reduction and the Preferred Stock ReductionIncrease shall become effective, automatically and without further action by the stockholders, upon the filing with the Delaware Secretary of State of an appropriate certificateCertificate of amendmentAmendment to the Charter (the "Charter Filing").Certificate of Incorporation. The complete text of such amendment is set forth in Exhibit A hereto. At any time prior to the effectivenessVOTING REQUIREMENT Approval of the Charter Filing (or, if no Charter Filing has been made, priorCommon Stock Increase requires the affirmative vote of the holders of stock representing a majority of the votes entitled to be cast at the Charter Filing), the Board of Directors may abandon the Charter Amendments without further action by the stockholders.Meeting. THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE FOR THE PROPOSED AMENDMENT TO THE CERTIFICATE OF INCORPORATION TO EFFECT THE COMMON STOCK INCREASE. 16 PROPOSAL TO APPROVE AND RATIFYNO. 3 - AMEND THE 1998 STOCK OPTION PLAN Reason for Submission to Stockholder This Proposal is being submitted to stockholders to comply with the terms of the Stock Purchase Agreement, to satisfy requirements of the Internal Revenue Code of 1986, as amended (the "Code"), and to satisfy the requirements of the NASDAQ Stock Market.REASONS FOR THE PLAN INCREASE The Proposal is one of the matters contained in the Plan of Recapitalization and Financing (the "Plan") which, pursuant to the Stock Purchase Agreement, is to be adopted by the Company and submitted to the Company's stockholders for their approval. The failure of the Company's stockholders to approve this Proposal would constitute a failure to approve the Plan and could have a material adverse effect on the business and financial condition of the Company. See "Background." Description of the 1998 Stock Option Plan On August 31, 1998, the Board of Directors, subject to stockholder approval, adopted the 1998 Stock Option Plan for employees, including officers, and directors of, and consultants and advisors to, the Company or any subsidiary corporation (aggregating approximately 27 persons as of October 1, 1998). A summary of the 1998 Stock Option Plan (the "Stock Option Plan""Plan") is set forth below. The summary is qualifiedwas adopted by the Board of Directors in its entiretyAugust 1998 and approved by reference tostockholders at a special meeting in December 1998. Currently, the full textPlan allows for a maximum of the Stock Option Plan, a copy of which is attached hereto as Exhibit B. The Stock Option Plan covers 20,000,0004,000,000 shares of Common Stock (subject to adjustment to cover stock splits, stock dividends, recapitalizations, and other capital adjustments, includingadjustments) to be issued pursuant to the ReversePlan. In contemplation of increasing the number of shares of Common Stock Split)covered by the Plan, and subject to approval of the Plan Increase by the stockholders of the Company, options were granted to employees and directors of and consultants to the Company over and above those currently authorized by the Plan. In order to honor the commitments made in connection with such grants, and to provide the Company with sufficient flexibility for future grants, the Board of Directors amended the Plan, subject to the approval of the Company's stockholders, to increase to 10,000,000 the maximum number of shares of Common Stock that may be issued pursuant to the Plan (subject to adjustment to cover stock splits, stock dividends, recapitalizations, and other capital adjustments). The proposal to approve the Plan Increase is now being submitted to stockholders for their approval. A summary of the Plan as proposed to be amended is set forth below. The summary does not purport to be complete and is qualified in its entirety by the text of the Plan as proposed to be amended, a copy of which is attached to this Proxy Statement as Annex B. SUMMARY OF PLAN The Plan covers 10,000,000 shares of Common Stock (subject to adjustment to cover stock splits, stock dividends, recapitalizations, and other capital adjustments). The options granted under the Stock Option Plan will beare designated as incentive stock options or non-incentive stock options by the Board of Directors or a committee thereof, which also will have discretion as to the persons to be granted options, the number of shares subject to the options, and the terms of the option agreements. Only employees (including officers) of the Company and its affiliates may be granted incentive stock options. The options to be granted under the Stock Option Plan and designated as incentive stock options are intended to receive incentive stock option tax treatment pursuant to Section 422 of the Code.Internal Revenue Code of 1986, as amended (the "Code"). The Stock Option Plan provides that all options thereunder shall be exercisable during a period of no more than ten years from the date of grant (five years for options granted to holders who own more than 10% of the total combined voting power of all classes of stock of the Company), depending upon the specific stock option agreement, and that the option exercise price for incentive stock options shall be at least equal to 100% of the fair market value of the Common Stock at the time of grant (110% for options granted to holders who own more than 10% of the total combined voting power of all classes of stock of the Company). In addition, the aggregate fair market value (determined on the date of grant) of the Common Stock with respect to which incentive stock options are exercisable for the first time by an employee during any calendar year shall not exceed $100,000. The Stock Option Plan permits optionees whose employment is terminated without cause and other than by 17 reason of death, disability or retirement at age 65, to exercise their options prior to the expiration thereof or within three months, or such longer period as the Board of Directors (or a committee thereof) may decide on a case by case basis, of termination, whichever is earlier, but only to the extent the holder had the right to exercise such options on the date of termination. If the employment of an optionee is terminated for cause and other than by reason of death, disability or retirement at age 65, any options granted to the optionee will terminate automatically. If employment is terminated by reason of disability or retirement at age 65, the optionee may exercise his options at any time prior to the expiration thereof or within one year from the date of termination (three months from the date of termination in the event of termination by reason of retirement at age 65), whichever is earlier, but only to the extent the holder had the right to exercise such options on the date of termination. If employment is terminated by death, the person or persons to whom the optionee's rights under the option are transferred by will or the laws of descent and distribution have similar rights of exercise within three months after such death (but not after the expiration of the option). Options are not transferable otherwise than by will or the laws of descent and distribution, or pursuant to a qualified domestic relations order as defined under the Code or Title I of the Employee Retirement Income Security Act or the rules thereunder, and are exercisable during the optionee's lifetime only by the optionee. Shares subject to options which expire or terminate may be the subject of future options. The Stock Option Plan terminates on August 30, 2008. If shares are issued to the holder of a non-incentive option under the Stock Option Plan (a) no income will be recognized by the holder at the time of grant of the option; (b) except as stated below, upon exercise of the option, the holder will recognize taxable ordinary income in an amount equal to the excess of the fair market value of the shares over the option price; (c) if the holder exercising the option is restricted from selling the shares so acquired because the holder is an officer or director of the Company and would be subject to liability under Section 16(b) of the Exchange Act, then, unless the holder makes an election to be taxed under the rule of clause (b) above, the holder will recognize taxable ordinary income, at the time such Section 16(b) restriction terminates, equal to the excess of the fair market value of the shares at that time over the option price, and any dividends he or she receives on the shares before that time will be taxable to him or her as income; (d) the Company will be entitled to a deduction at the same time and in the same amount as the holder has income under clause (b) or (c); and (e) upon a sale of shares so acquired, the holder may have additional short-term or long-term capital gain or loss. If shares are issued to the holder of an incentive stock option under the Stock Option Plan, (a) no income will be recognized by such holder at the time of the grant of the option or the transfer of shares to the holder pursuant to his or her exercise of the option; (b) the difference between the option price and the fair market value of the shares at the time of exercise will be treated as an item of tax preference to the holder; (c) no deduction will be allowed to the Company for federal income tax purposes in connection with the grant or exercise of the option; and (d) upon a sale or exchange of the shares after the later of (i) one year from the date of transfer of the shares to the original holder, or (ii) two years from the date of grant of the option, any amount realized by the holder in excess of the option price will be taxed to the holder as a long- termlong-term capital gain, and any loss sustained by the holder will be a long-term capital loss. If the shares are disposed of before the holding period requirements described in the preceding sentence are satisfied, (aa) the holder will recognize taxable ordinary income in the year of disposition in an amount determined under the rules of the Code; (bb) the Company will be entitled to a deduction for such year in the amount 18 of the ordinary income so recognized; (cc) the holder may have additional long-term or short-term capital gain or loss; and (dd) the tax preference provision might not be applicable. The Stock Option Plan provides for the cashless payment of the exercise price of options granted under the Stock Option Plan by (a) delivery to the Company of shares of Common Stock having a fair market value equal to such purchase price, (b) irrevocable instructions to a broker to sell shares of Common Stock to be issued upon exercise of the option, followed by delivery to the Company of the amount of sale proceeds necessary to pay such purchase price, and delivery of the remaining cash proceeds less commissions and brokerage fees to the optionee or delivery of the remaining shares of Common Stock to the optionee, or (c) by any combination of the methods of payment described in (a) and (b) above. Voting Requirement ApprovalThe Plan also provides that in the event any distribution consists of securities (including common stock) held by the Company in any subsidiary or any other company, then (i) with respect to securities of a subsidiary, each holder of options under the Plan on the record date for such distribution shall be entitled to receive options to purchase such number of such securities as is equal to the number of securities such holder would have received had he exercised all of his options under the Plan (vested and unvested) and owned the common stock in the Company underlying such options, which options in the subsidiary shall be vested or shall vest to the same extent as such holder's options in the Company, and, generally, shall contain such provisions as to put such holder in the same equitable position such holder was in prior to the distribution, including an allocation of the proposalexercise price for the options issued under this Plan to ratifyboth such option and approve the Stock Optionoptions in the subsidiary, and (ii) with respect to securities of another company, each holder of options under the Plan requires affirmative voteon the record date for such distribution shall be entitled to receive such number of securities as such holder would have received had he exercised all of his options under the holders ofPlan (vested and unvested) and owned the common stock representing a majority ofin the Company underlying such options, which securities shall be vested or shall vest to the same extent as such holder's options in the Company. To the extent such securities do not vest in the holder, they shall be retained by the Company. If the shares presentof Common Stock outstanding are changed in personnumber, kind, or representedclass by proxy atreason of a stock split, combination, merger, consolidation, reorganization, reclassification, exchange, or any capital adjustment, including a stock dividend, or if any distribution is made to stockholders other than a cash dividend and the Meeting and entitled to vote thereon. The Board of Directors recommends(or Committee) deems it appropriate to make an adjustment, then (i) the aggregate number and class of shares that may be issued under the stockholders vote FOR ratificationPlan, (ii) the number and approvalclass of shares which are issuable under outstanding options, and (iii) the Plan. PROPOSAL TO APPROVE THE STOCK OPTION/WARRANT GRANT Reason for Submissionpurchase price to Stockholders This Proposal is being submitted to stockholders to comply with the terms of the Stock Purchase Agreement and to satisfy the requirements of the NASDAQ Stock Market. The Proposal is one of the matters containedbe paid per share under outstanding options, shall be adjusted in a Plan of Recapitalizationproportionate and Financing (the "Plan") which, pursuant to the Stock Purchase Agreement, is to be adopted by the Company's Board of Directors and submitted to the Company's stockholders for their approval. The failure of the Company's stockholders to approve this Proposal would constitute a failure to approve the Plan and could have a material adverse effect on the business and financial condition of the Company. See "Background." Reason for the Stock Option/Warrant Grant In connection with the adoption and approval of the Planequitable manner by the Board of Directors, andDirectors. In the event of a liquidation of the Company, or a merger, reorganization, or consolidation of the Company with any other corporation in which the Company is not the surviving corporation or the Company becomes a wholly-owned subsidiary of another corporation, any unexercised options theretofore granted under the Plan shall be deemed canceled unless the surviving corporation in any such merger, reorganization, or consolidation elects to assume the options under the Plan or to issue substitute options in place thereof; provided, however, if such options would otherwise be canceled in accordance with the foregoing, the optionee shall have the right, 19 exercisable during a ten-day period immediately prior to such liquidation, merger, or consolidation, to exercise the option, in whole or in part. The granting of an option pursuant to the terms thereof,Plan shall not affect in any way the Boardright or power of Directors granted, on a pre-Reverse Stock Split basis: (i)the Company to make adjustments, reorganizations, reclassifications, or changes of its capital or business structure or to merge, consolidate, dissolve, liquidate, or sell or transfer all or any part of its business or assets. NEW PLAN BENEFITS For each of the Named Executive Officers and the various indicated groups, the table below shows the benefits that will be allocated to each of the following under the 1998 Stock Option Plan, stock options to purchase an aggregate of 13,300,000 shares of Common Stock, at $.25 per share, to: Richard J. Reinhart, Ph.D.,plan being acted upon. NUMBER OF NAME AND PRINCIPAL POSITION OPTION SHARES (1) DOLLAR VALUE - ---------------------------------------- ----------------- ------------ John G. Baust President and Chief Executive Officer and Director1,000,000 $80,000 Executive group (1 persons) 1,000,000 $80,000 Non-executive director group (3 persons) 750,000 $60,000 Non-executive officer employee group (7 persons) 910,000 $72,800 - 7,200,000; John Baust, Ph.D., Senior Vice President and Chief Scientific Officer - 2,160,000; Alan F. Rich, Vice President - Sales and Marketing - 1,100,000; an aggregate of 14 employees - 775,000,; Howard S. Breslow, Director - 720,000 and J. Donald Hill, Director - 720,000, (ii) warrants to purchase 2,880,000 shares of---------- (1) Stock options exercisable at $.08 per share The closing price per share for the Common Stock at $.25 per share,as reported on the OTC Bulletin Board on July 25, 2005 was $0.16. 20 EQUITY COMPENSATION PLAN INFORMATION Number of securities available for Number of future issuance securities to Breslow & Walker, LLP, the Company's general counsel,be under equity issued upon Weighted average compensation plans exercise of which Howard S. Breslow, a directorexercise price of the Company is a member,(excluding outstanding outstanding securities options, warrants options, warrants reflected in Plan Category and (iii) warrants to purchase 3,600,000 shares of Common Stock, at $.25 per share, to BWM Investments, of which Howard S. Breslow, a director of the Company, is a partner, to appropriately incentivize and/or compensate them for services provided to the Company.rights and rights column (a) - ------------- ----------------- ----------------- ------------------ (a) (b) (c) Equity compensation plan approved by shareholders 2,906,000 $0.52 -0- Equity compensation plan not approved by shareholders 29,926,858 $0.19 4,449,000 ---------- ----- --------- Total 32,832,858 $0.22 4,449,000 ========== ===== ========= VOTING REQUIREMENT The Company believes that it has been only through the efforts of management, the Board of Directors, and the Company's legal counsel (and its affiliates) that the Company has maintained its viability under some very trying and difficult circumstances. Approval of the Stock Option/Warrant GrantPlan Increase requires the affirmative vote of the holders of stock representing a majority of shares present in person or represented by proxy at the Meeting and entitled to vote thereon. Voting RequirementTHE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE FOR THE PROPOSED AMENDMENT TO THE PLAN TO EFFECT THE PLAN INCREASE. 21 PROPOSAL NO. 4 - RATIFICATION OF THE APPOINTMENT OF INDEPENDENT AUDITORS The Board of Directors recommends thathas selected the stockholders vote FORaccounting firm of Aronson & Company to serve as the Company's independent auditors for the year ending December 31, 2005 and proposes the ratification of such decision. Aronson & Company has audited the Company's financial statements for the year ended December 31, 2004. Representatives of Aronson & Company are expected to be present at the Annual Meeting, with the opportunity to make a statement if they desire to do so, and approvalto respond to appropriate questions. During 2004, Aronson & Company acted as the independent auditors for the Company. The following table sets forth the aggregate fees billed by Aronson & Company for audit and review services rendered in connection with the financial statements and reports for the years ending December 31, 2004 and December 31, 2003 and for other services rendered during the years ending December 31, 2004 and December 31, 2003 on behalf of the Stock Option/Warrant Grant. PROPOSAL TO APPROVE THE SEC FILING Reason for Submission to Stockholders This Proposal is being submitted to stockholders to comply with the termsCompany: 2004 2003 ------- ------- Audit Fees $49,275 $64,317 Audit-related fees -0- -0- Tax fees 6,775 17,163 All other fees 475 -0- ------- ------- Total $56,525 $81,480 The Board of the Stock Purchase Agreement. The Proposal is one of the matters contained in a Plan of RecapitalizationDirectors pre-approves all audit and Financing (the "Plan") which, pursuant to the Stock Purchase Agreement, isnon-audit services to be adoptedperformed by the Company's Board of Directors and submitted to the Company's stockholders for their approval. The failureindependent auditors. VOTING REQUIREMENT Ratification of the Company's stockholders to approve this Proposal would constitute a failure to approve the Plan and could have a material adverse effect on the business and financial conditionappointment of the Company. See "Background." The failure of the Company's stockholders to approve this Proposal would not preclude the Company from filing a registration statement with the Securities and Exchange Commission ("SEC") for the sale of securities by the Company. Reason for the SEC Filing Subject to the adoption of the Plan by the Company and its stockholders, ValorInvest has agreed to use its best efforts to arrange for a public offering ("Public Offering") (contemplated to be in Europe) of the Company's securities through an underwriter (the "Underwriter"), to be designated or approved by ValorInvest. Through ValorInvest, the Company has obtained a letter of interest for a Public Offering from a German Underwriter. The letter does not contain any commitment for a Public Offering, and any Public Offering by such Underwriter, at the very least, would be subject to the completion of due diligence by such Underwriter and market conditions. The terms of a Public Offering, if any, would be as negotiated between the Company and the Underwriter. There can be no assurance that a Public Offering will be consummated. The consummation of the Public Offering would require the filing of a registration statement with the SEC. In addition, the Company has covenanted to include the shares of Common Stock issuable upon conversion of the Series E Preferred Stock purchased pursuant to the Stock Purchase Agreement in the registration statement at the Company's cost and expense, and to keep such registration statement effective until such time or such shares of Common Stock may be sold pursuant to an exemption from registration pursuant to the Securities Act of 1933, as amended. Accordingly, the Plan contains an undertaking by the Company that it will prepare and file a registration statement with the SEC for the sale of securities of the Company on such terms and conditions as may be mutually agreed to between the Company and an underwriter to be designated or approved by ValorInvest. Voting Requirement Approval of the SEC Filingindependent auditors requires the affirmative vote of the holders of stock representing a majority of shares present in person or represented by proxy at the Meeting and entitled to vote thereon. The Board of Directors recommends that the stockholders voteTHE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE FOR ratification and approval of the SEC Filing.THE RATIFICATION OF THE APPOINTMENT OF THE INDEPENDENT AUDITORS. 22 PRINCIPAL STOCKHOLDERS The following table sets forth, as of October 1, 1998, certain information regarding the beneficial ownership of Common Stock and Preferred Stock by (i) each stockholder known by the Company to be the beneficial owner of more than 5% of the outstanding shares thereof; (ii) each director of the Company; (iii) each executive officer of the Company; and (iv) all of the Company's directors and executive officers as a group.
Title of ClassName and Address of Beneficial Owner S Amount and Nature of Beneficial Ownership(1) S Percentage of Class (1) Common Stock Richard R. Reinhart, Ph.D.*/** 1300 Piccard Drive, Suite 102 Rockville, MD 20850 1,000,000(2) 2.9% Common Stock John G. Baust, Ph.D.* 1300 Piccard Drive, Suite 102 Rockville, MD 20850 400,000(3) 1.1% Common Stock Alan F. Rich* 1300 Piccard Drive, Suite 102 Rockville, MD 20850 185,500(4) *** Common Stock Howard S. Breslow, Esq. ** c/o Breslow & Walker, LLP 767 Third Avenue New York, NY 10017 268,000(5) *** Common Stock J. Donald Hill** 1300 Piccard Drive, Suite 102 Rockville, MD 20850 75,000(6) *** Preferred Stock ValorInvest, Ltd. 29 Quai des Berges 1201 Geneva, Switzerland 128 100% Common Stock All officers and directors as a group (five persons) 1,928,500(7) 5.6% Preferred Stock All officers and directors as a group (five persons) - - 0 - - 0 -____________________
(1) Shares of Common Stock subject to options and warrants currently exercisable or exercisable within 60 days are deemed outstanding for computing the number of shares and the percentage of the outstanding shares held by a person holding such options or warrants, but are not deemed outstanding for computing the percentage of any other person. Except as indicated by footnote, and subject to community property laws where applicable, the Company believes that the persons named in the table have sole voting and investment power with respect to all shares of Common Stock shown as beneficially owned by them. (2) Includes 1,000,000 shares of Common Stock issuable upon the exercise of outstanding stock options. (3) Includes 380,000 shares of Common Stock issuable upon the exercise of outstanding stock options. (4) Includes 180,000 shares of Common Stock issuable upon the exercise of outstanding stock options. (5) Includes 100,000 shares of Common Stock issuable upon the exercise of outstanding stock options. (6) Consists of 75,000 shares of Common Stock issuable upon the exercise of outstanding stock options. (7) Includes 1,735,000 shares of Common Stock issuable upon the exercise of outstanding stock options. * Executive Officer. ** Director. ***Less than 1%. INTEREST OF CERTAIN PERSONS The Stock Purchase Agreement with ValorInvest requiresIN MATTERS TO BE ACTED UPON John G. Baust, the Chief Executive Officer of the Company, and Messrs. Breslow, deGreef and Girschweiler, directors of the Company, have an interest in the approval of the Plan Increase. On May 12, 2005, the Board of Directors of the Company granted to adopt a Plan of Recapitalization and Financing (the "Plan") and to submit the Plan to stockholders for their approval. In connection with the adoption and approval by the Board of Directors of the Plan, and pursuant to the terms thereof, the Board of Directors granted, on a pre-Reverse Stock Split basis: (i) under the 1998 Stock Option Plan, stock(a) Dr. Baust ten-year options to purchase an aggregate of 13,300,0001,000,000 shares of Common Stock at $.25a price of $.08 per share, including grantswhich options shall vest to the following executive officers and directorsextent of 250,000 shares on the first day of the Company: Richard J. Reinhart, Ph.D., President, Chief Executive Officermonth following the first anniversary date of the grant (the "First Vesting Date") and Director - 7,200,000; John G. Baust, Ph.D.,Senior Vice President20,833 on the first day of each of the next 36 months following the First Vesting Date, and Chief Scientific Officer - 2,160,000; Alan F. Rich, Vice President-Sales and Marketing - 1,100,000; Howard S. Breslow, Director - 720,000; and J. Donald Hill, Director - 720,000, (ii) warrants(b) to each of the aforesaid directors a ten-year, fully vested non-incentive stock option to purchase 2,880,000250,000 shares of Common Stock at $.25a price of $0.08 per share,share; provided, however, that such stock options may not be exercised until such time as (x) the amendment to Breslow & Walker, LLP, the Company's general counsel,Stock Option Plan, approved by the Company's Board of Directors on October 12, 2004, increasing the number of shares of Common Stock covered by Plan from 4,000,000 shares to 7,500,000 shares (subsequently increased to 10,000,000 shares) is approved by the Company's stockholders, which Howard S. Breslow, a directorapproval must take place on or before October 12, 2005 (and in the event such approval does not take place on or before October 12, 2005, the options are rescinded), and (y) the certificate of incorporation of the Company is a member, and (iii) warrantsamended to purchase 3,600,000increase the authorized number of shares of Common Stock,common stock to a number that is sufficient to accommodate the exercise of all options granted to them. STOCKHOLDER PROPOSALS Stockholder proposals for action at $.25 per share, to BWM Investments,the Company's Annual Meeting of which Howard S. Breslow, a director ofStockholders for the Company, is a partner, to appropriately incentivize and/or compensate them for services providedfiscal year ending December 31, 2004 must be submitted in writing to the Company at its address set forth on the first page of this Proxy Statement and received by the Company no later than June 1, 2005 in each case subjectorder that they may be considered for inclusion in the proxy statement and form of proxy relating to approvalthat meeting. Stockholders who intend to present a proposal at the Company's Annual Meeting of Stockholders for the year ending December 31, 2004 without inclusion of such proposal in the Company's proxy materials are required to provide notice of such proposal to the Company no later than August 1, 2005. The Company reserves the right to reject, rule out of order, or take other appropriate action with respect to any proposal that does not comply with these and other applicable requirements. SECTION 16(a) BENEFICIAL OWNERSHIP COMPLIANCE The Company's officers, directors and beneficial owners of more than 10% of any class of its equity securities registered pursuant to Section 12 of the Plan by the stockholdersSecurities Exchange Act of 1934 ("Reporting Persons") are required under that Act to file reports of ownership and changes in beneficial ownership of the Company's equity securities with the Securities and Exchange Commission. Copies of those reports must also be furnished to the Company. Based solely on a review of the copies of reports furnished to the Company pursuant to that Act, the Company believes that during the fiscal year ended December 31, 2004, all filing requirements applicable to Reporting Persons were complied with. 23 OTHER MATTERS The Board of Directors of the Company does not know of any other matters that are to be presented for action at the Meeting. Should any other matters properly come before the Meeting or any adjournments thereof, the persons named in the enclosed proxy will have the discretionary authority to vote all proxies received with respect to such matters in accordance with their judgment. STOCKHOLDER PROPOSALS TO BE PRESENTED AT THE COMPANY'S NEXT ANNUAL MEETING OF STOCKHOLDERS Stockholder proposals intended to be presented at the next Annual Meeting of Stockholders of the Company must be received by the Company, at its principal executive offices, within a reasonable time prior to the solicitation of proxies in connection with such meeting in order for such proposals to be included in the Proxy Statement and Proxy relating to such meeting. This Proxy Statement is sent by order of the Board of Directors of the Company. Richard J. Reinhart, Ph.D.,-------------------------- John G. Baust President and Chief Executive Officer Rockville, Maryland November 2, 1998Owego, New York August 26, 2005 STOCKHOLDERS ARE URGED TO SPECIFY THEIR CHOICES AND DATE, SIGN, AND RETURN THE ENCLOSED PROXY IN THE ENCLOSED ENVELOPE. A PROMPT RESPONSE IS HELPFUL AND YOUR COOPERATION WILL BE APPRECIATED. 24 EXHIBITANNEX A - ------- CERTIFICATE OF AMENDMENT OF THE CERTIFICATE OF INCORPORATION OF CRYOMEDICAL SCIENCES,BIOLIFE SOLUTIONS, INC. ----------------------- (Pursuant to Section 242 of the General Corporation Law of the State of Delaware) Cryomedical Sciences,BioLife Solutions, Inc. (the "Corporation"), a corpo- rationcorporation organized and existing under the General Corporation Law of the State of Delaware (the "GCL"), certifies as follows: 1. The name of the Corporation is Cryomedical Sciences,BioLife Solutions, Inc. 2. The date of filing of the Corporation's certificate of incorporation (the "Certificate of Incorporation") with the Secretary of State of the State of Delaware was November 5, 1987. 3. Subdivision (a) of Article Fourth of the Certificate of Incorporation is hereby amended so that it shall now read as follows: "FOURTH: (a) The totalaggregate number of shares of stock which the Corporation shall have the authority to issue is 25,000,000shall be: One hundred million (100,000,000) shares of common stock, each having a par value of $.001 (the "Common Stock"), and 1,000,000one million (1,000,000) shares of preferred stock, each having a par value of $.001 (the "Preferred Stock"). The Board of Directors, is expressly authorizedin its sole discretion, shall have full and complete authority, by resolution, from time to provide for the issuance of alltime, to establish one or anymore series or classes and to issue shares of Preferred Stock, in one or more classes or series, and to fix, for each such class or series suchdetermine and vary the voting powers, full or limited, or non-voting powers, and such distinctiverights, designations, preferences, restrictions, qualifications, privileges, limitation, options, conversion rights and relative, participating, optional, or other special rights of each series or class of Preferred Stock, including, but not limited to, dividend rates and such qualifications, limitations,manner of payment, preferential amounts payable upon voluntary or restrictions thereof, as shall be statedinvoluntary liquidation, voting rights, conversion rights, redemption prices, terms and expressed in the resolution or resolutions adopted by the Board of Directors providing for the issuance of such class or series and as may be permitted by the GCL, including, without limitation, the authority to provide that any such class or series may be (i) subject to redemption at such time or times and at such price or prices; (ii) entitled to receive dividends (which may be cumulative or non-cumulative) at such rates, on such conditions, and at such times,sinking fund and payable in preference to, or in such relation to, the dividends payable on any other class or classes or any other series; (iii) entitled to such rights upon the dissolution of, or upon any distribution of the assets of, the Corporation; or (iv) convertible into, or exchangeable for, shares of any other classes of stock of the Corporation at such price orpurchase prices, or at such rates of exchangeterms and with such adjustments; all as may be stated in such resolution or resolutions.conditions." 4. Upon the filing in the Office of the Secretary of State of the State of Delaware of a Certificate of Amendment to the Certificate of Incorporation of the Corporation whereby this Article Fourth is amended to read as set forth herein (the "Filing"), each ___________ shares of Common Stock issued and outstanding and held of record by each stockholder of the Corporation immediately prior to the Filing shall, automatically and without the need for any further action on the part of any stockholder, be combined into one (1) validly issued, fully paid, and non-assessable share of Common Stock, par value $.001 per share. No scrip or fractional shares will be issued by reason of this amendment, but, in lieu thereof, one whole share will be issued to those stockholders who would otherwise be entitled to receive fractional shares. 5. This Certificate of Amendment to the Certificate of Incorporation was authorized by the affirmative vote of the holders of a majority of the outstanding shares entitled to vote thereon at a meeting of stockholders pursuant to Sections 222 and 242 of the GCL. IN WITNESS WHEREOF, I hereunto sign my name and affirm that the statements made herein are true under penalties of perjury this ____ day of _________________, 1998. CRYOMEDICAL SCIENCES,2005. BIOLIFE SOLUTIONS, INC. By Richard J. Reinhart, Ph.D.,By: ____________________________ John G. Baust, President and Chief Executive Officer 2 EXHIBITANNEX B CRYOMEDICAL SCIENCES,------- BIOLIFE SOLUTIONS, INC. 1998 STOCK OPTION PLAN (as amended May 10, 2001) 1. Purpose of Plan.PURPOSE OF PLAN. The purpose of this 1998 Stock Option Plan (the "Plan") is to further the growth and development of Cryomedical Sciences,BioLife Solutions, Inc. (the "Company") by encouraging and enabling employees, officers, and directors of, and consultants and advisors to, the Company to obtain a proprietary interest in the Company through the ownership of stock (thereby providing such persons with an added incentive to continue in the employ or service of the Company and to stimulate their efforts in promoting the growth, efficiency, and profitability of the Company), and affording the Company a means of attracting to its service persons of outstanding quality. 2. Shares of Stock Subject to the Plan.SHARES OF STOCK SUBJECT TO THE PLAN. Subject to the provisions of Section 12 hereof, an aggregate of 20,000,00010,000,000 shares of the common stock, par value $.001 per share, of the Company ("Common Stock") shall be reserved for issuance upon the exercise of options which may be granted from time to time in accordance with the Plan. As the Board of Directors of the Company ("Board of Directors") shall from time to time determine, such shares may be, in whole or in part, authorized but unissued shares or issued shares which have been reacquired by the Company. If, for any reason, an option shall lapse, expire, or terminate without having been exercised in full, the unpurchased shares underlying such option shall (unless the Plan shall have been terminated) again be available for issuance pursuant to the Plan. 3. Administration.ADMINISTRATION. (a) The Board of Directors shall administer the Plan and, subject to the provisions of the Plan, shall have authority to determine and designate from time to time those persons eligible for a grant of options under the Plan, those persons to whom options are to be granted, the purchase price of the shares covered by each option, the time or times at which options shall be granted, and the manner in which said options are exercisable. In making such determination, the Board of Directors may take into account the nature of the services rendered by the respective persons, their present and potential contributions to the Company's success, and such other factors as the Board of Directors in its sole discretion shall deem rele- vant.relevant. Subject to the express provisions of the Plan, the Board of Directors also shall have authority to interpret the Plan, to prescribe, amend, and rescind rules and regulations relating to the Plan, to determine the terms and provisions of the instruments by which options shall be evidenced (which shall not be inconsistent with the terms of the Plan), and to make all other determinations necessary or advisable for the administration of the Plan, all of which determinations shall be final, binding, and conclusive. (b) The Board of Directors may, at its discretion, in accordance with the provisions of the Company's By-Laws, appoint from among its members a Stock Option or Compensation Committee (the "Committee"). The Committee shall be composed of two or more directors and shall have and may exercise any and all of the powers relating to the administration of the Plan and the grant of options hereunder as are set forth above in Section 3(a), as the Board of Directors shall confer and delegate. The Board of Directors shall have the power at any time to fill vacancies in, to change the membership of, or to discharge, the Committee. The Committee shall select one of its members as its Chairman and shall hold its meetings at such time and at such places as it shall deem advisable. A majority of the Committee shall constitute a quorum and such majority shall determine its action. The Committee shall keep minutes of its proceedings and shall report the same to the Board of Directors at the meeting next succeeding. No director or member of the Committee shall be liable for any action or determination made in good faith with respect to the Plan or any option granted thereunder. 4. Persons To Whom Shares May Be Granted.PERSONS TO WHOM SHARES MAY BE GRANTED. (a) Options may be granted to persons who are, at the time of the grant, employees (including part-time employees), officers, and directors of, or consultants or advisors to, the Company or any subsidiary corporation (as defined in Section 425 of the Internal Revenue Code of 1986, as amended (the "Code"), a "Subsidiary") as the Board of Directors (or Committee) shall select from time to time from among those nominated by the Board of Directors (or Committee). For the purposes of the Plan, options only may be granted to those consultants and advisors who shall render bona fide services to the Company and such services must not be in connection with the offer or sale of securities in a capital raising transaction. Subject to the provisions hereinafter set forth, options granted under the Plan shall be designated either (i) "Incentive Stock Options" (which term, as used herein, shall mean options intended to be "incentive stock options" within the meaning of Section 422 of the Code) or (ii) "Non-Incentive Stock Options" (which term, as used herein, shall mean options not intended to be incentive stock options" within the meaning of Section 422 of the Code). Each option granted to a person who is solely a director of, or consultant or advisor to, the Company or a Subsidiary on the date of the grant shall be designated a Non-Incentive Stock Option. (b) The Board of Directors (or Committee) may grant, at any time, new options to a person who has previously received options, whether such prior options are still outstanding, have previously been exercised in whole or in part, have expired, or are canceled in connection with the issuance of new options. The purchase price of the new options may be established by the Board of Directors (or Committee) without regard to the existing option price. 5. Option Price.OPTION PRICE. (a) The purchase price of the Common Stock underlying each option shall be determined by the Board of Directors (or Committee), which determination shall be final, binding, and conclusive; provided, however, in no event shall the purchase price of Incentive Stock Options be less than 100% (110% in the case of optionees who own more than 10% of the total combined voting power of all classes of stock of the Company) of the fair market value of the Common Stock on the date the option is granted. In determining such fair market value, the Board of Directors (or Committee) shall consider (i) the last sale price of the Common Stock on the date on which the option is granted or, if no such reported sale takes place on such day, the last reported bid price on such day, on NASDAQ or on the principal national securities exchange on which the Common 2 Stock is admitted to trading or listed, or (ii) if not listed or admitted to trading on NASDAQ or a national securities exchange, the closing bid price as quoted by the National Quotation Bureau or a recognized dealer in the Common Stock on the date of grant. If the Common Stock is not publicly traded at the time an option is granted, the Board of Directors (or Committee) shall deem fair market value to be the fair value of the Common Stock after taking into account appropriate factors which may be relevant under applicable federal tax laws and Internal Revenue rules and regulations. For purposes of the Plan, the date of grant of an option shall be the date specified by the Board of Directors (or Committee) at the time it grants such option; provided, however, such date shall not be prior to the date on which the Board of Directors (or Committee) acts to approve the grant. (b) The aggregate fair market value (determined at the time the Incentive Stock Options are granted) of the Common Stock with respect to which Incentive Stock Options are exercisable for the first time by an employee during any calendar year shall not exceed $100,000. Non-Incentive Stock Options shall not be subject to the limitations of this paragraph 5(b). 6. Exercise of Options.EXERCISE OF OPTIONS. (a) The number of shares which are issued pursuant to the exercise of an option shall be charged against the maximum limitations on shares set forth in Section 2 hereof. (b) The exercise of an option shall be made contingent upon receipt by the Company from the holder thereof of (i) if deemed necessary by the Company, a written representation and acknowledgement that (1) at the time of such exercise it is the holder's then present intention to acquire the option shares for investment and not with a view to distribution or resale thereof, (2) the holder knows that the Company is not obligated to register the option shares and that the option shares may have to be held indefinitely unless an exemption from the registration requirements of the Securities Act of 1933, as amended (the "Act"), is available or the Company has registered the shares underlying the options, and (3) the Company may place a legend on the certificate(s) evidencing the option shares reflecting the fact that they were acquired for investment and cannot be sold or transferred unless registered under the Act, and (ii) payment in full of the purchase price of the shares being purchased. Payment may be made in cash; by certified check payable to the order of the Company in the amount of such purchase price; by delivery to the Company of shares of Common Stock having a fair market value equal to such purchase price; by irrevocable instructions to a broker to sell shares of Common Stock to be issued upon exercise of the option and to deliver to the Company the amount of sale proceeds necessary to pay such purchase price and to deliver the remaining cash proceeds, less commissions and brokerage fees, to the optionee; or by any combination of such methods of payment. 7. Term of Options.TERM OF OPTIONS. The period during which each option granted hereunder shall be exercisable shall be determined by the Board of Directors (or Committee); provided, however, no option shall be exercisable for a period exceeding ten (10) years from the date such option is granted. 8. Non-Transferability of Options.NON-TRANSFERABILITY OF OPTIONS. No option granted pursuant to the Plan shall be subject to 3 anticipation, sale, assignment, pledge, encumbrance, or charge, or shall be otherwise transferable except by will or the laws of descent and distribution or pursuant to a qualified domestic relations order (as defined by the Code or Title I of the Employee Retirement Income Security Act or the rules thereunder), and an option shall be exercisable during the lifetime of the holder thereof only by such holder. 9. Termination of Services.TERMINATION OF SERVICES. If an employee, officer, or director to whom an option has been granted under the Plan shall cease to be an employee, officer, or director of the Company or a Subsidiary by reason of a termination of such relationship without cause and other than by reason of death or disability, such holder may exercise such option at any time prior to the expiration date of the optionoptions or within three months (or such longer period as the Board of Directors (or Committee) may decide on a case by case basis) after the date of termination, whichever is earlier, but only to the extent the holder had the right to exercise such option on the date of termination. If an employee, officer, or director to whom an option has been granted under the Plan shall cease to be an employee, officer, or director of the Company or a Subsidiary by reason of a termination of such relationship for cause and other than by reason of death or disability, such options shall terminate, lapse, and expire forthwith and automatically. So long as the holder of an option shall continue to be in the employ, or continue to be a director, of the Company or one or more of its Subsidiaries, such holder's option shall not be affected by any change of duties or position. Absence on leave approved by the employing corporation shall not be considered an interruption of employment for any purpose under the Plan. The granting of an option in any one year shall not give the holder of the option any rights to similar grants in future years or any right to be retained in the employ or service of the Company or any of its Subsidiaries or interfere in any way with the right of the Company or any such Subsidiary to terminate such holder's employment or services at any time. Notwithstanding the foregoing, no option may be exercised after ten years from the date of its grant. 10. Disability of Holder of Option.DISABILITY OF HOLDER OF OPTION. If any employee, officer, or director to whom an option has been granted under the Plan shall cease to be an employee, officer, or director of the Company or a Subsidiary by reason of disability, such holder may exercise such option at any time prior to the expiration date of the option or within one year after the date of termination for such reason, whichever is earlier, but only to the extent the holder had the right to exercise such option on the date of termination. Notwithstanding the foregoing, no option may be exercised after ten years from the date of its grant. For the purposes of the Plan, "disability" shall mean "permanent and total disability" as defined in Section 22(e)(3) of the Code. 11. Death of Holder of Option.DEATH OF HOLDER OF OPTION. If any employee, officer, or director to whom an option has been granted under the Plan shall cease to be an employee, officer, or director of the Company or a Subsidiary by reason of death, or such holder of an option shall die within three months after termination, or in the case of the death of an advisor or consultant to whom an option has been granted under the Plan, the option may be exercised by the person or persons to whom the optionee's rights under the option are transferred by will or by the laws of descent and distribution at any time prior to the expiration date of the option or, in the case of an employee, officer, or director, within three months from the date of death, whichever is earlier, but only to the extent the holder of the option had the right to exercise such option on the date of such termination. Notwithstanding the foregoing, no option may be exercised after ten years from the date of its grant. 4 12. Adjustments Upon Changes in Capitalization.ADJUSTMENTS UPON CHANGES IN CAPITALIZATION. (a) If the shares of Common Stock outstanding are changed in number, kind, or class by reason of a stock split, combination, merger, consolidation, reorganization, reclassification, exchange, or any capital adjustment, including a stock dividend, or if any distribution is made to stockholders other than a cash dividend and the Board of Directors (or Committee) deems it appropriate to make an adjustment, then (i) the aggregate number and class of shares that may be issued or transferred pursuant to Section 2, (ii) the number and class of shares which are issuable under outstanding options, and (iii) the purchase price to be paid per share under outstanding options, shall be adjusted as hereinafter provided. In the event any distribution consists of common stock held by the Company in any subsidiary, then each holder of options under this Plan on the record date for such distribution shall be entitled to receive options to purchase such number of shares of such common stock as is equal to the number of shares of common stock such holder would have received had such holder exercised all of such holder's options under this Plan (vested and unvested) and owned the common stock in the Company underlying such options, which options in the subsidiary shall be vested or shall vest to the same extent as such holder's options in the Company, and, generally, shall contain such provisions as to put such holder in the same equitable position such holder was in prior to the distribution, including an allocation of the exercise price for the options issued under this Plan to both such options and the options in the subsidiary. (b) Adjustments under this Section 12 shall be made in a proportionate and equitable manner by the Board of Directors (or Committee), whose determination as to what adjustments shall be made, and the extent thereof, shall be final, binding, and conclusive. In the event that a fraction of a share results from the foregoing adjustment, said fraction shall be eliminated and the price per share of the remaining shares subject to the option adjusted accordingly. (c) In the event of a liquidation of the Company, or a merger, reorganization, or consolidation of the Company with any other corporation in which the Company is not the surviving corporation or the Company becomes a wholly-owned subsidiary of another corporation, any unexercised options theretofore granted under the Plan shall be deemed canceled unless the surviving corporation in any such merger, reorganization, or consolidation elects to assume the options under the Plan or to issue substitute options in place thereof; provided, however, if such options would otherwise be canceled in accordance with the foregoing, the optionee shall have the right, exercisable during a ten-day period immediately prior to such liquid- ation,liquidation, merger, or consolidation, to exercise the option, in whole or in part. The granting of an option pursuant to the Plan shall not affect in any way the right or power of the Company to make adjustments, reorganizations, reclassifications, or changes of its capital or business structure or to merge, consolidate, dissolve, liquidate, or sell or transfer all or any part of its business or assets. 13. Vesting of Rights Under Options.VESTING OF RIGHTS UNDER OPTIONS. Nothing contained in the Plan or in any resolution adopted or to be adopted by the Board of Directors (or Committee) or the stockholders of the Company shall constitute the vesting of any rights under any option. The vesting of such rights shall take place only when a written agreement shall be duly executed and delivered by and on 5 behalf of the Company to the person to whom the option shall be granted. 14. Rights as a Stockholder.RIGHTS AS A STOCKHOLDER. A holder of an option shall have no rights of a stockholder with respect to any shares covered by such holder's option until the date of issuance of a stock certificate to such holder for such shares. 15. Termination and Amendment.TERMINATION AND AMENDMENT. The Plan was adopted by the Board of Directors on August 31, 1998, subject, with respect to the validation of Incentive Stock Options granted under the Plan, to approval of the Plan by the stockholders of the Company at the next Meeting of Stockholders or, in lieu thereof, by written consent. If the approval of stockholders is not obtained prior to August 30 1999, any grants of Incentive Stock Options under the Plan made prior to that date will be rescinded. The Plan shall expire at the end of the day on August 30, 2008 (except as to options outstanding on that date). Options may be granted under the Plan prior to the date of stockholder approval of the Plan. The Board of Directors (or Committee) may terminate or amend the Plan in any respect at any time, except that, without the approval of the stockholders obtained within 12 months before or after the Board of Directors (or Committee) adopts a resolution authorizing any of the following actions, (a) the total number of shares that may be issued under the Plan may not be increased (except by adjustment pursuant to paragraph 12); (b) the provisions regarding eligibility for grants of Incentive Stock Options may not be modified; (c) the provisions regarding the exercise price at which shares may be offered pursuant to Incentive Stock Options may not be modified (except by adjustment pursuant to paragraph 12), and (d) the expiration date of the Plan may not be extended. Except as otherwise provided in this paragraph 15, in no event may action of the Board of Directors (or Committee) or stockholders alter or impair the rights of an optionee, without such optionee's consent, under any option previously granted to such optionee. 16. Modification, Extension and Renewal of Options.MODIFICATION, EXTENSION AND RENEWAL OF OPTIONS. Subject to the terms and conditions and within the limita- tionslimitations of the Plan, the Board of Directors (or Committee) may modify, extend, or renew outstanding options granted under the Plan, or accept the surrender of outstanding options (to the extent not theretofore exercised) and authorize the granting of new options in substitution therefor. Notwithstanding the foregoing, no modification of an option shall, without the consent of the holder thereof, alter or impair any rights or obligations under any option theretofore granted under the Plan. 17. Conversion of Incentive Stock Options into Non- Qualified Options.CONVERSION OF INCENTIVE STOCK OPTIONS INTO NON-QUALIFIED OPTIONS. Without the prior written consent of the holder of an Incentive Stock Option, the Board of Directors (or Committee) shall not alter the terms of such Incentive Stock Option (including the means of exercising such Incentive Stock Option) if such alteration would constitute a modification within the meaning of Section 424(h)(3) of the Code. The Board of Directors (or Committee), at the written request or with the written consent of any optionee, may in its discretion take such actions as may be necessary to convert such optionee's Incentive Stock Options (or any installments or portions of installments thereof) that have not been exercised on the date of conversion into Non- IncentiveNon-Incentive Stock Options at any time prior to the expiration of such Incentive Stock Options, regardless of whether the optionee is an employee of the Company at the time of such conversion. Such actions may include, but shall not be limited to, extending the exercise period or reducing the exercise price of the appropriate installments of such Incentive Stock Options. At the time of such conversion, the 6 Board of Directors (or Committee) (with the consent of the optionee) may impose such conditions on the exercise of the resulting Non-Incentive Stock Options as the Board of Directors (or Committee) in its discretion may determine, provided that such conditions shall not be inconsistent with the Plan. Nothing in the Plan shall be deemed to give any optionee the right to have such optionee's Incentive Stock Options converted into Non- IncentiveNon-Incentive Stock Options, and no such conversion shall occur until and unless the Board of Directors (or Committee) takes appropriate action. 18. Withholding of Additional Income Taxes.WITHHOLDING OF ADDITIONAL INCOME TAXES. Upon the exercise of a Non-Incentive Stock Option, the transfer of a Non-Incentive Stock Option pursuant to an arm's length transaction, the making of a Disqualifying Disposition (as described in Sections 421, 422 and 424 of the Code and regulations thereunder), the vesting of transfer of restricted stock or securities acquired on the exercise of an option hereunder, or the making of a distribution or other payment with respect to such stock or securities, the Company may withhold taxes in respect of amounts that constitute compensation includible in gross income. The Board of Directors (or Committee) in its discretion may condition the exercise of an option, the transfer of a Non-Incentive Stock Option, or the vesting or transferability of restricted stock or securities acquired by exercising an option on the optionee's making satisfactory arrangement for such withholding. Such arrangement may include payment by the optionee in cash or by check of the amount of the withholding taxes or, at the discretion of the Board of Directors (or Committee), by the optionee's delivery of previously held shares of Common Stock or the withholding from the shares of Common Stock otherwise deliverable upon exercise of option shares having an aggregate fair market value equal to the amount of such withholding taxes. 19. Indemnification.INDEMNIFICATION. In addition to such other rights of indemnification as they may have as members of the Board of Directors (or Committee), the members of the Board of Directors (or Committee) administering the Plan shall be indemnified by the Company against reasonable expenses, including attorneys' fees, actually and necessarily incurred in connection with the defense of any action, suit, or proceeding, or in connection with any appeal therein, to which they or any of them may be a party by reason of any action taken or failure to act under or in connection with the Plan or any option granted thereunder, and against all amounts paid by them in settlement thereof (provided such settlement is approved by independent legal counsel selected by the Company) or paid by them in satisfaction of a judgment in any action, suit, or proceeding, except in relation to matters as to which it shall be adjudged in such action, suit, or proceeding that such member is liable for negligence or misconduct in the performance of his duties, and provided that within 60 days after institution of any such action, suit, or proceeding, the member shall in writing offer the Company the opportunity, at its own expense, to handle and defend the same. 20. Governing Law.GOVERNING LAW. The validity and construction of the Plan and the instruments evidencing options shall be governed by the laws of Delaware, or the laws of any jurisdiction in which the Company or its successors in interest may be organized. 7 PRELIMINARY COPYBIOLIFE SOLUTIONS, INC. 171 FRONT STREET OWEGO, NY 13827 THIS PROXY CRYOMEDICAL SCIENCES, INC. 1300 Piccard Drive, Suite 102 Rockville, Maryland 20850 This Proxy is solicited on behalf of the Board of DirectorsIS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS The undersigned, acknowledging receipt of the proxy statement dated November 2, 1998August 26, 2005 of Cryomedical Sciences,BioLife Solutions, Inc., hereby constitutes and appoints Richard J. ReinhartJohn G. Baust and J. Donald Hill,Howard S. Breslow and each or any of them, attorney, agent and proxy of the undersigned, with full power of substitution to each of them, for and in the name, place and stead of the undersigned on the books of said corporation, to appear and vote all the shares of stock of Cryomedical Sciences,BioLife Solutions, Inc., standing in the name of the undersigned on the books of said corporation on October 23, 1998August 19, 2005, at the SpecialAnnual Meeting of Stockholders of Cryomedical Sciences,BioLife Solutions, Inc., to be held at the offices of the Company, 1300 Piccard Drive, Suite 102, Rockville, Maryland 20850,Breslow & Walker, LLP, 767 Third Avenue, New York, NY 10017 on December 16, 1998September 28, 2005, at 10:00 a.m.A.M., Maryland time,Eastern Standard Time, and any and all adjournments thereof. When properly executed, this proxy will be voted as designated by the undersigned. If no choice is specified, thisthe proxy will be voted (i) FOR approval of the proposed Amendmentfollowing proposals, which are set forth in the Proxy Statement. 1. ELECTION OF DIRECTORS _______ For all nominees listed below (except as marked to the Company's Certificate of Incorporation ("Charter")contrary below) _______ Withhold Authority to effectvote for all nominees listed below John G. Baust Howard S. Breslow Rod de Greef Thomas Girschweiler (INSTRUCTION: to withhold authority to vote for any individual nominee, strike a one-for-five, one for six, one for seven, one for eight, one for nine, one for ten, one for eleven, one for twelve, one for thirteen, one for fourteen, one for fifteen,line through or one for sixteen reverse stock split ofotherwise strike nominee's name in the issued and outstanding shares of Common Stock, with one of such approved alternatives to be chosen by the Board of Directors of the Company (the "Reverse Stock Split"list above.), (ii) FOR the approval of the proposed amendment to the Charter to reduce the number of authorized shares of Common Stock from 50,000,000 shares to 25,000,000 shares (the "Common Stock Reduction"), (iii) FOR the approval of the proposed amendment to the Charter to reduce the number of authorized shares of Preferred Stock of the Company, par value $.001 per share ("Preferred Stock"), from 9,378,800 shares to 1,000,000 shares (the "Preferred Stock Reduction"), (iv) FOR ratification and approval of the Company's 1998 Stock Option Plan (the "1998 Stock Option Plan"), (v) FOR ratification and approval of the grant of stock options/warrants for 19,155,000 shares (pre- Reverse Stock Split), exercisable at $.25 per share (pre-Reverse Stock Split) to management, others who have performed services for the Company, and directors, to appropriately incentivize and compensate them (the Stock Option/Warrant Grant"), and (vi) FOR approval of the preparation and filing of a registration statement with the Securities and Exchange Commission for the sale of securities by the Company (the "SEC Filing"). A vote to ABSTAIN with respect to a particular matter will have the same effect as a vote AGAINST a particular matter. 1. PROPOSAL TO AMEND THE CHARTER TO EFFECT THE REVERSE STOCK SPLIT. ( ) FOR ( ) AGAINST ( ) ABSTAIN 2. PROPOSAL TO AMEND CHARTERAPPROVE AN AMENDMENT TO EFFECT THE COMPANY'S CERTIFICATE OF INCORPORATION TO INCREASE THE NUMBER OF AUTHORIZED SHARES OF COMMON STOCK REDUCTION. ( ) FOR ( ) AGAINST ( ) ABSTAINFROM 25,000,000 TO 100,000,000. FOR____ AGAINST____ ABSTAIN____ 3. PROPOSAL TO AMEND CHARTERAPPROVE AN AMENDMENT TO EFFECT THE PREFERREDCOMPANY'S 1998 STOCK REDUCTION. ( )OPTION PLAN TO INCREASE THE NUMBER OF SHARES OF COMMON STOCK RESERVED FOR ( ) AGAINST ( ) ABSTAINISSUANCE THEREUNDER FORM 4,000,000 TO 10,000,000. FOR____ AGAINST____ ABSTAIN____ 4. PROPOSAL TO RATIFY AND APPROVE THE 1998 STOCK OPTION PLAN. ( )APPOINTMENT OF ARONSON & COMPANY TO SERVE AS INDEPENDENT AUDITORS FOR ( ) AGAINST ( ) ABSTAINTHE YEAR ENDING DECEMBER 31, 2005. FOR____ AGAINST____ ABSTAIN____ 5. PROPOSAL TO APPROVEVOTE, IN THE STOCK OPTION/WARRANT GRANT. ( ) FOR ( ) AGAINST ( ) ABSTAIN 6. PROPOSAL TO APPROVEDISCRETION OF THE SEC FILING. ( ) FOR ( ) AGAINST ( ) ABSTAIN 7. FORPROXIES, ON SUCH OTHER MATTERS THAT MAY PROPERLY COME BEFORE THE MEETING AND ANY ADJOURNMENTS THEREOF. Date Print Name Signature Signature, if held jointlyPlease sign exactly as name appears below. When shares are held by joint tenants, both should sign. When signing as attorney, administrator, trustee or guardian, please give full title as such. If a corporation, please sign in full corporate name by President or other authorized officer. If a partnership, please sign in partnership name by authorized person. DATED: ,2005 ------------------ ------------------------------ Signature ------------------------------- Signature if held jointly PLEASE MARK, SIGN, DATE AND RETURN THISTHE PROXY CARD PROMPTLY IN THE ENCLOSED ENVELOPE. Dear Shareholder: Since the announcement of the Company's Plan of Recapitalization and Financing (the "Plan"), I have been inundated with calls from stockholders with questions about the Plan. The Plan was adopted by the Board of Directors of the Company in accordance with the terms and conditions of a Stock Purchase Agreement (the "Agreement") with ValorInvest, Ltd. ("ValorInvest"). The Agreement requires that the Plan be submitted to the Company's stockholders for their approval. The enclosed proxy material contains a great deal of information regarding the Plan. We hope that this material will answer any questions you may have. However, if you still have questions regarding the Plan after you have reviewed the proxy material, please give me a call at the Company at (301) 417-7070 extension 222. This is an important enough issue that I am going to make myself available over the next several weeks to answer any questions you may have. If I am unable to take your call immediately, please leave a message containing your name, telephone number and a time that I can get back to you. Due to the fact that the Company is unable to contact its many shareholders on a one on one basis I am taking this opportunity to make you aware of the primary consideration that the Company has in regard to the approval of the Plan. It is most important that you realize the following: 21. The Plan consists of six individual matters. 22. Each matter is individually itemized on the proxy voting card. 23. In order for the Plan to be "approved", all six of these matters must be approved. 24. If you elect to abstain or vote against any one of these matters your overall vote will be considered to be "against" the Plan. It is important that you understand that if the Plan is not approved by the Company's stockholders, then, at the request of ValorInvest, the Company must redeem the Series E Units purchased by ValorInvest pursuant to the Agreement at the price paid therefor plus a penalty. ANY SUCH REQUEST BY VALORINVEST WOULD HAVE A MATERIAL ADVERSE EFFECT ON THE BUSINESS AND FINANCIAL CONDITION OF THE COMPANY. Your management team, together with the Board of Directors and the Company's counsel, have worked very hard to maintain the viability of the Company over the past year. It is imperative that we get stockholder approval of the Plan. We look forward to your support. Sincerely, Richard J. Reinhart, Ph.D. President and CEOENVELOPE